1-Iodo-3-nitrobenzene

CAS: 645-00-1

Ref. TR-I715615

Información del producto

• Nombre: 1-Iodo-3-nitrobenzene
• Sinónimos: 3-Iodo-1-nitrobenzene, 3-Iodonitrobenzene, 3-Nitro-1-iodobenzene, 3-Nitroiodobenzene, 3-Nitrophenyl Iodide, NSC 3538, m-Iodonitrobenzene, m-Nitroiodobenzene, m-Nitrophenyl Iodide, 3-Nitrophenyl iodide, Benzene, 1-iodo-3-nitro-, m-Nitrophenyl iodide

Descripción

Applications 1-Iodo-3-nitrobenzene is a reactant used int he synthesis of Vismodegib (V674700), an, antineoplastic drug that targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cao, M., et. al.: Chem. Papers, 68, 1408 (2014); Gupta, S. et al.: Ther. Advances in Med. Oncology 2,237(2010)

• Marca: TRC

Propiedades químicas

• Peso molecular: 249.01
• Fórmula: C₆H₄INO₂
• Color/Forma: Neat
• InChI: InChI=1S/C6H4INO2/c7-5-2-1-3-6(4-5)8(9)10/h1-4H
• Clave InChI: InChIKey=OBQFYRYCMDREFB-AKIFATBCSA-N
• SMILES: O=C1[C@H](CC[C@H](O)c2ccccc2F)[C@@H](c2ccc(O)cc2)N1c1ccc(F)cc1