Isotetrandrine

CAS: 477-57-6

Ref. TR-I918015

Información del producto

• Nombre: Isotetrandrine
• Sinónimos: Isosinomenin A, Isosinomenine A, NSC 97338, O,O-Dimethylobamegine, O,O-Dimethylstepholine, O,O'-Dimethylobamegine, O,O'-Dimethylstepholine, O-Methylberbamine, [4aS-(4aR*,16aS*)]-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, (R,S)-Tetrandrine, (4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 6,6',7,12-Tetramethoxy-2,2'-dimethyl-berbaman, (1Beta,1'Beta)-6,6',7,12-Tetramethoxy-2,2'-Dimethylberbaman, (4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 1-Isotetrandrine, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aR)-, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, [4aS-(4aR*,16aS*)]-, 6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman, 8,19,20,25-Tetramethoxy-14,30-Dimethyl-6,22-Dioxa-14,30-Diazaheptacyclo[22.6.2.2~2,5~.1~7,11~.1~13,17~.0~21,33~.0~27,31~]Hexatriaconta-2,4,7(34),8,10,17(33),18,20,24,26,31,35-Dodecaene (Non-Preferred Name), Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl- (9CI), Berbaman, 6,6′,7,12-tetramethoxy-2,2′-dimethyl-, Ccris 6540, Nsc 97338

Descripción

Applications Isotetrandrine is a biscoclaurine alkaloid inhibitor of G protein activation of PLA2.
References Abe, T., et al.: Toxicon, 38, 1803 (2003); Matsuno, T., et al.: Biochem. Pharmacol., 36, 1613 (1987); Matsuno, T., et al.: Igaku to Yakugaku, 16, 445 (1986)

• Marca: TRC

Propiedades químicas

• Peso molecular: 622.75
• Fórmula: C₃₈H₄₂N₂O₆
• Color/Forma: Neat
• InChI: InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30+/m0/s1
• Clave InChI: InChIKey=DKGAVHZHDRPRBM-SGLLWXCUSA-N
• SMILES: [2H]OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]