LCZ696 Sodium Salt Hydrate

CAS: 1884447-69-1

Ref. TR-L270005

Información del producto

• Nombre: LCZ696 Sodium Salt Hydrate
• Sinónimos: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine, compound with a-Ethyl (aR,gS)-g-[(3-carboxy-1-oxopropyl)amino]-a-methyl[1,1'-biphenyl]-4-pentanoate, Sodium Salt, Hydrate (2:2:6:5), Entresto, Sacubitril-valsartan
• CAS: 1884447-69-1

Descripción

Applications LCZ696 is a novel dual-acting inhibitor of angiotensin II receptor and neprilysin, which can be used for blood pressure reduction.
References Ruilope, L.M.; et al.: Lancet, 375, 1255 (2010)

• Marca: TRC

Propiedades químicas

• Peso molecular: 479.48 + (433.47) + x(18.02)
• Fórmula: C₂₄H₂₇N₅Na₂O₃•CH₂₈NNaO₅•xH₂O
• Color/Forma: Off White Crystalline Powder
• InChI: InChI=1S/C24H29N5O3.C24H29NO5.3Na.H2O/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23;1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;;;;/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H2,25,26,27,28,31,32);4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);;;;1H2/q;;3*+1;/p-3/t22-;17-,21+;;;;/m01..../s1
• Clave InChI: InChIKey=PHVGTMDCHAQCRO-LWRBNZNASA-K
• SMILES: CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnnn2[Na])cc1)[C@H](C(=O)O[Na])C(C)C.CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)CCC(=O)O[Na]