Leuprolide Acetate

CAS: 88793-81-1

Ref. TR-L330600

Información del producto

• Nombre: Leuprolide Acetate
• Sinónimos: 6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamideluteinizing Hormone-Releasing Factor Acetate(Pig), A 43818, Abbott 43818, Leuprorelin Acetate, Lupron, Procren Depot, Procrin, Prostap, TAP 144, TAP 144SR
• CAS: 88793-81-1

Descripción

Applications Synthetic nonapeptide agonist analog of LH-RH. Antineoplastic (hormonal).
References Vilchez-Martinez, J.A., et al.: Biochem. Biophys. Res. Commun., 59, 1226 (1974), Sennello, L.T., et al.: J. Pharm. Sci., et al.: 75, 158 (1986), Wheeler, J.M., et al.: Am.J. Obstet. Gynecol., 167, 1367 (1992), Eri, L.M., et al.: J. Urol., 150, 359 (1993),

• Marca: TRC

Propiedades químicas

• Peso molecular: 1209.42 + x(60.05)
• Fórmula: C₅₉H₈₄N₁₆O₁₂•xC₂H₄O₂)
• Color/Forma: White to Off-White Solid
• InChI: InChI=1S/C59H84N16O12.C2H4O2/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40;1-2(3)4/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64);1H3,(H,3,4)/t40-,41-,42-,43+,44-,45-,46-,47-,48-;/m0./s1
• Clave InChI: InChIKey=RGLRXNKKBLIBQS-LSTPZILBSA-N
• SMILES: CC(=O)O.CCNC(=O)[C@H]1CCCN1C(=O)C(CCCNC(=N)N)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1