Linagliptin Methyl Dimer

CAS: 668270-12-0

Ref. TR-L465945

Información del producto

• Nombre: Linagliptin Methyl Dimer
• Sinónimos: Linagliptin Impurity, 8-(3-Aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-(2-((1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)ethyl)quinazolin-2-yl)methyl)-3-methyl-1H-purine-2,6(3H,7H)-dione, (R)-8-[3-Aminopiperidin-1-yl]-7-(2-butynyl)-3-methyl-1-(4-methylquinazolin-2-ylmethyl)xanthine, 1H-Purine-2,6-Dione, 8-[(3R)-3-Amino-1-Piperidinyl]-7-(2-Butyn-1-Yl)-3,7-Dihydro-3-Methyl-1-[(4-Methyl-2-Quinazolinyl)Methyl]-, 1H-Purine-2,6-dione, 8-[(3R)-3-amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-, 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione, 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione, 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione, Bi 1356, Bi 1356Bs, Ondero, Tradjenta, Trajenta, Trazenta
• CAS: 668270-12-0

Descripción

Applications Linagliptin Methyldimer is an impurity of Linagliptin (L465900). Linagliptin is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011)

• Marca: TRC

Propiedades químicas

• Peso molecular: 957.095
• Fórmula: C₅₁H₅₆N₁₆O₄
• Color/Forma: Neat
• InChI: InChI=1S/C51H56N16O4/c1-6-8-26-64-42-44(58-48(64)62-24-14-16-33(52)28-62)60(4)51(71)67(47(42)69)31-41-56-38-21-13-11-19-36(38)39(57-41)22-23-53-34-17-15-25-63(29-34)49-59-45-43(65(49)27-9-7-2)46(68)66(50(70)61(45)5)30-40-54-32(3)35-18-10-12-20-37(35)55-40/h10-13,18-21,33-34,53H,14-17,22-31,52H2,1-5H3/t33-,34-/m1/s1
• Clave InChI: InChIKey=OTMSDBZUPAUEDD-UHFFFAOYSA-N
• SMILES: CC#CCn1c(N2CCCC(NCCc3nc(Cn4c(=O)c5c(nc(N6CCCC(N)C6)n5CC#CC)n(C)c4=O)nc4ccccc34)C2)nc2c1c(=O)n(Cc1nc(C)c3ccccc3n1)c(=O)n2C