Lubiprostone-d7

CAS: 1217675-13-2

Ref. TR-L473503

Información del producto

• Nombre: Lubiprostone-d7
• Sinónimos: (11a)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid-d7, Ru 0211-d7

Descripción

Applications Labelled Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.
References Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (2001), Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (2002), Coremans, G., et al.: Digestion, 67, 82 (2003),

• Marca: TRC

Propiedades químicas

• Peso molecular: 397.51
• Fórmula: C₂₀H₂₅D₇F₂O₅
• Color/Forma: Neat
• InChI: InChI=1S/C20H32F2O5/c1-2-3-12-20(21,22)18(25)11-10-15-14(16(23)13-17(15)24)8-6-4-5-7-9-19(26)27/h14-15,17,24H,2-13H2,1H3,(H,26,27)/t14-,15-,17-/m1/s1/i1D3,2D2,3D2
• Clave InChI: InChIKey=DBVFKLAGQHYVGQ-QHZIEZROSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CC(F)(F)C(=O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O