1-(3-Methoxypropyl)-4-piperidinamine

CAS: 179474-79-4

Ref. TR-M227270

Información del producto

• Nombre: 1-(3-Methoxypropyl)-4-piperidinamine
• Sinónimos: 1-(3-methoxypropyl)piperidin-4-amine, 1-(3-Methoxypropyl)piperidin-4-amine, 4-Piperidinamine, 1-(3-methoxypropyl)-

Descripción

Applications 1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008); McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009); Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008); Yuan, Y., et al.: Zhongguo Yiyao Gongye Zazhi, 43, 5 (2012)

• Marca: TRC

Propiedades químicas

• Peso molecular: 172.268
• Fórmula: C₉H₂₀N₂O
• Color/Forma: Colourless To Light Yellow
• InChI: InChI=1S/C9H20N2O/c1-12-8-2-5-11-6-3-9(10)4-7-11/h9H,2-8,10H2,1H3
• Clave InChI: InChIKey=HIXAJGFVNMKLML-UHFFFAOYSA-N
• SMILES: COCCCN1CCC(N)CC1