Mertansine-13CD3

CAS: 139504-50-0

Ref. TR-M257802

Información del producto

• Nombre: Mertansine-13CD3
• Sinónimos: N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine-13CD3, DM 1-13CD3, Maytansinoid DM 1-13CD3, N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine-13CD3, Mertansine, DM 1, N2′-Deacetyl-N2′-(3-mercapto-1-oxopropyl)maytansine, Maytansine, N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-, Maytansinoid DM 1

Descripción

Stability Hygroscopic
Applications Mertansine-13CD3 is the isotope labelled analog of Mertansine (M257800); a cytotoxic agent used as the cytotoxic component in antibody-drug conjugates.
References Erickson, H., et al.: Cancer Res., 66, 4426 (2006); Kellogg, B., et al.: Bioconjugate Chem., 22, 717 (2011)

• Marca: TRC

Propiedades químicas

• Peso molecular: 742.3
• Fórmula: C₃₄₁₃CH₄₅D₃ClN₃O₁₀S
• Color/Forma: White To Off-White
• InChI: InChI=1S/C35H48ClN3O10S/c1-19-10-9-11-26(46-8)35(44)18-25(47-33(43)37-35)20(2)31-34(4,49-31)27(48-32(42)21(3)38(5)28(40)12-13-50)17-29(41)39(6)23-15-22(14-19)16-24(45-7)30(23)36/h9-11,15-16,20-21,25-27,31,44,50H,12-14,17-18H2,1-8H3,(H,37,43)/b11-9-,19-10-/t20-,21+,25+,26-,27+,31-,34+,35+/m1/s1/i5+1D3
• Clave InChI: InChIKey=ANZJBCHSOXCCRQ-BAHKDAGBSA-N
• SMILES: [2H][13C]([2H])([2H])N(C(=O)CCS)[C@@H](C)C(=O)O[C@H]1CC(=O)N(C)c2cc(cc(OC)c2Cl)C/C(C)=C/C=C/[C@@H](OC)[C@@]2(O)C[C@H](OC(=O)N2)[C@@H](C)[C@H]2O[C@@]12C