1-Methyl Adenosine-d3

CAS: 15763-06-1

Ref. TR-M285067

Información del producto

• Nombre: 1-Methyl Adenosine-d3
• Sinónimos: (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-imino-1-methyl-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diol-d3, (6Z)-1-methyl-9-pentofuranosyl-1,9-dihydro-6H-purin-6-imine, 1-Methyladenosine, 9H-Purine, 1,6-dihydro-6-imino-1-methyl-9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, Adenosine, 1-methyl-, Adenosine, 1-methyl- (VAN) (8CI), Adenosine, N,6-didehydro-1,6-dihydro-1-methyl- (9CI), N1-Methyladenosine, N¹-Methyladenosine, Nsc 92165

Descripción

Applications 1-Methyl Adenosine-d3 is the isotope labelled analog of 1-Methyl Adenosine (M285065); a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.
References Wu, Q. et al.: Anal. Chem., 86, 10122 (2014); Puri, P. et al.: Mol. Microbiol., 93, 944 (2014)

• Marca: TRC

Propiedades químicas

• Peso molecular: 284.29
• Fórmula: C₁₁H₁₂D₃N₅O₄
• Color/Forma: Neat
• InChI: InChI=1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1/i1D3
• Clave InChI: InChIKey=GFYLSDSUCHVORB-YZLHILBGSA-N
• SMILES: [2H]C([2H])([2H])n1cnc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1=N