2'-(N-Methylanthraniloyl) Guanosine 3',5'-Cyclic Monophosphate Sodium Salt

CAS: 221905-46-0

Ref. TR-M288250

Información del producto

• Nombre: 2'-(N-Methylanthraniloyl) Guanosine 3',5'-Cyclic Monophosphate Sodium Salt
• Sinónimos: Cyclic 3',5'-(hydrogen phosphate) 2'-[2-(methylamino)benzoate] Guanosine Monosodium Salt, MANT-cGMP

Descripción

Applications A blue fluorescent derivative of cGMP is a useful substrate the assay of cyclic nucleotide phosphdiesterase. Also inhibits calmodulin-dependent activation of cyclic nucleotide phosphodiesterase by peptide segments of HIV envelope glycoproteins has been monitored using MANT-cGMP.Fluorescence: max. Abs. 359nm; max. Em. 448nm; e x 10-3: 5.2
References J. Biol. Chem., 257, 13354 (1982), Anal. Biochem., 162, 291 (1987), J. Biol. Chem., 270, 22277 (1993)

• Marca: TRC

Propiedades químicas

• Peso molecular: 500.33
• Fórmula: C₁₈H₁₈N₆NaO₈P
• Color/Forma: Pale Yellow Solid
• InChI: InChI=1S/C18H19N6O8P.Na/c1-20-9-5-3-2-4-8(9)17(26)31-13-12-10(6-29-33(27,28)32-12)30-16(13)24-7-21-11-14(24)22-18(19)23-15(11)25;/h2-5,7,10,12-13,16,20H,6H2,1H3,(H,27,28)(H3,19,22,23,25);/q;+1/p-1/t10-,12-,13-,16-;/m1./s1
• Clave InChI: InChIKey=YSPAKCFRSSBJJK-KHXPSBENSA-M
• SMILES: CNc1ccccc1C(=O)O[C@@H]1[C@@H]2OP(=O)(O[Na])OC[C@H]2O[C@H]1n1cnc2c(=O)[nH]c(N)nc21