N(1-(3-Methylbutanamido) N(1-Des(boric Acid)) Bortezomib

CAS: 862894-96-0

Ref. TR-M294055

Información del producto

• Nombre: N(1-(3-Methylbutanamido) N(1-Des(boric Acid)) Bortezomib
• Sinónimos: 2-Pyrazinecarboxamide, N-[(1S)-2-[(3-methyl-1-oxobutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-, Pyrazinecarboxamide, N-[(1S)-2-[(3-methyl-1-oxobutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-, N-[(1S)-1-Benzyl-2-(3-methylbutanoylamino)-2-oxo-ethyl]pyrazine-2-carboxamide, N-[(1S)-1-Benzyl-2-(3-methylbutanoylamino)-2-oxoethyl]pyrazine-2-carboxamide

Descripción

Applications N(1-(3-Methylbutanamido) N(1-Des(boric Acid)) Bortezomib is an impurity of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);

• Marca: TRC

Propiedades químicas

• Peso molecular: 354.403
• Fórmula: C₁₉H₂₂N₄O₃
• Color/Forma: White To Off-White
• InChI: InChI=1S/C19H22N4O3/c1-13(2)10-17(24)23-18(25)15(11-14-6-4-3-5-7-14)22-19(26)16-12-20-8-9-21-16/h3-9,12-13,15H,10-11H2,1-2H3,(H,22,26)(H,23,24,25)/t15-/m0/s1
• Clave InChI: InChIKey=WREPYMVPDVCLPX-HNNXBMFYSA-N
• SMILES: CC(C)CC(=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1