5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride

CAS: 720720-96-7

Ref. TR-M330085

Información del producto

• Nombre: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride
• Sinónimos: 4,5,6,7-Tetrahydro-5-methylthiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride, 4,5,6,7-Tetrahydro-5-methylthiazolo[5,4-c]pyridine-2-carboxylic Acid Monochloride, 5-Methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride, 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride, 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride(for Edoxaban), 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid HCl, 4,5,6,7-Tetrahydro-5-Methyl-Thiazolo[5,4-C]Pyridine-2-Carboxylic Acid Hcl, 4,5,6,7-tetrahydro-5-Methy-Thiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride, 5-Methyl-4,5,6,7-tetra hydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride

Descripción

Stability Hygroscopic
Applications 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is used as a reagent in the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclylmethyl)thiophene-2-carboxamide derivatives as antithrombotics. It is also used as a reagent in the synthesis of diamide derivatives as FXa inhibitors. 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is an intermediate for Edoxaban (E555520).
References Mochizuki, A., et al.: Jpn. Kokai Tokkyo Koho. JP 2010120852 A 20100603. Jun 3, 2010; Mochizuki, A., et al.: PCT Int. Appl. WO 2008123017 A1 20081016. Oct 16, 2008

• Marca: TRC

Propiedades químicas

• Peso molecular: 234.7
• Fórmula: C₈H₁₁ClN₂O₂S
• Color/Forma: Light Brown
• InChI: InChI=1S/C8H10N2O2S.ClH/c1-10-3-2-5-6(4-10)13-7(9-5)8(11)12;/h2-4H2,1H3,(H,11,12);1H
• Clave InChI: InChIKey=ZWIYEBIMFPQYDI-UHFFFAOYSA-N
• SMILES: CN1CCc2nc(C(=O)O)sc2C1.Cl