3-Methyl-3-phenyl-2-oxiranecarboxylic Acid Methyl Ester

CAS: 5441-04-3

Ref. TR-M338665

Información del producto

• Nombre: 3-Methyl-3-phenyl-2-oxiranecarboxylic Acid Methyl Ester
• Sinónimos: α,β-Epoxy-β-methyl-hydrocinnamic Acid Methyl Ester, 3-Methyl-3-phenyl-oxiranecarboxylic Acid Methyl Ester
• Marca: TRC
• Descripción: Applications 3-Methyl-3-phenyl-2-oxiranecarboxylic Acid Methyl Ester is an intermediate in the synthesis of 4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan (Mixture of Diastereomers) (D460510). 4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan (Mixture of Diastereomers) is a related compound of Ambrisentan (A575860) used as endothelin receptor antagonist in treating cancer.References Nelson, J., et al.: Nature Med., 1, 944 (1995); Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996)

Propiedades químicas

• Peso molecular: 192.21
• Fórmula: C₁₁H₁₂O₃
• Color/Forma: Brown
• InChI: InChI=1S/C11H12O3/c1-11(8-6-4-3-5-7-8)9(14-11)10(12)13-2/h3-7,9H,1-2H3
• Clave InChI: InChIKey=AGZSSAGYWIIPFE-UHFFFAOYSA-N
• SMILES: COC(=O)C1OC1(C)c1ccccc1