Mevinolinic Acid, Monoammonium Salt

CAS: 77550-67-5

Ref. TR-M340538

Información del producto

• Nombre: Mevinolinic Acid, Monoammonium Salt
• Sinónimos: Mevinolinic Acid, Monoammonium Salt, 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-ß,d-dihydroxy-2,6-dimethyl-8-[(2S)-2-methyl-1-oxobutoxy]-, ammonium salt (1:1), (ßR,dR,1S,2S,6R,8S,8aR)-, 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-ß,d-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxob

Descripción

Applications Mevinolinic Acid, Monoammonium Salt can be used as reactant/reagent in process for the preparation of the Simvastatin precursor, 2,2-dimethylbutanoic acid (1S,3R,7S,8S,8aR)-8-[(3R,5R)-7-(cyclopropylamino)-3,5-dihydroxy-7-oxoheptyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, via an amidation reaction.
References Khanna, J., et al.: Indian, IN 184809 A1 20000930 (2000)

• Marca: TRC

Propiedades químicas

• Peso molecular: 439.585
• Fórmula: C₂₄H₃₇O₆·H₄N
• Color/Forma: Neat
• InChI: InChI=1S/C24H38O6.H3N/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28, 1H3/t14-,15-,16-,18+,19+,20-,21-,23-, /m0./s1, /h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28)
• Clave InChI: InChIKey=AOIIYQZTRFOGNN-AXHZAXLDSA-N
• SMILES: CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@H]21.N