6alpha-Naloxol

CAS: 20410-95-1

Ref. TR-N284495

Información del producto

• Nombre: 6alpha-Naloxol
• Sinónimos: (4R,4aS,7S,7aR,12bS)-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol, (5alpha,6alpha)-4,5-Epoxy-17-(2-propenyl)morphinan-3,6,14-triol, (5α,6α)-4,5-Epoxy-17-(2-propen-1-yl)morphinan-3,6,14-triol, 6-Hydroxynaloxone, 6α-Naloxol, En 2265, Morphinan-3,6,14-triol, 4,5-epoxy-17-(2-propen-1-yl)-, (5α,6α)-, Morphinan-3,6,14-triol, 4,5-epoxy-17-(2-propenyl)-, (5α,6α)-, Morphinan-3,6α,14-triol, 17-allyl-4,5α-epoxy-, N-Allyl-14-hydroxy-7,8-dihydronormorphine, N-Allyl-7,8-dihydro-14-hydroxynormorphine, α-Naloxol

Descripción

Applications 6α-Naloxol is a metabolite of Naloxone (N285000), a specific opioid antagonist. Narcotic antagonist.
References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975); Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996); Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000); Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)

• Marca: TRC

Propiedades químicas

• Peso molecular: 329.39
• Fórmula: C₁₉H₂₃NO₄
• Color/Forma: Neat
• InChI: InChI=1S/C19H23NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,13-14,17,21-23H,1,5-10H2/t13-,14+,17-,18-,19+/m0/s1
• Clave InChI: InChIKey=HMWHERQFMBEHNG-AQQQZIQISA-N
• SMILES: C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](O)CC[C@@]3(O)[C@H]1C5