β-Nicotinic Acid Mononucleotide-d4

CAS: 321-02-8

Ref. TR-N429393

Información del producto

• Nombre: β-Nicotinic Acid Mononucleotide-d4
• Sinónimos: 3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium Inner Salt-d4, 3-Carboxy-1-β-D-ribofuranosylpyridinium Hydroxide 5'-Phosphate Inner Salt-d4, Nicotinate Mononucleotide-d4, Nicotinate Ribonucleotide-d4, Nicotinic Acid Ribonucleotide-d4, Nicotinic Acid Ribotide-d4, Nicotinic Mononucleotide-d4, β-NaMN-d4
• Marca: TRC

Descripción

Stability Hygroscopic
Applications β-Nicotinic Acid Mononucleotide-d4 is the isotope labelled analog of β-Nicotinic Acid Mononucleotide (N429390); a nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.
References Petrelli, R. et al.: Curr. Med. Chem., 18, 1973 (2011); Shibata, K. et al.: J. Chrom. B Biomed. Sci. Appl., 749, 281 (2000); Evans, C. et al.: BMC Chem. Biol., 10, 2 (2010)

Propiedades químicas

• Peso molecular: 339.23
• Fórmula: C₁₁H₁₀D₄NO₉P
• Pureza: >90%
• Color/Forma: Neat
• SMILES: [2H]c1c([2H])c([2H])[n+]([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c([2H])c1C(=O)[O-]