Nobiletin

CAS: 478-01-3

Ref. TR-N633500

Información del producto

• Nombre: Nobiletin
• Sinónimos: 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-, Flavone, 3',4',5,6,7,8-hexamethoxy- (7CI,8CI), Nobiletin (6CI), 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one, 3',4',5,6,7,8-Hexamethoxyflavone, 5,6,7,8,3',4'-Hexamethoxyflavone, NSC 618903, NSC 76751, 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one, 3′,4′,5,6,7,8-Hexamethoxyflavone, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-, 5,6,7,8,3′,4′-Hexamethoxyflavone, Ccris 9012, Flavone, 3′,4′,5,6,7,8-hexamethoxy-, Hexamethoxyflavone, Nsc 76751, Pmf 90

Descripción

Stability Light Sensitive
Applications Nobiletin is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. It is a potent antioxidant with good bioavailability. Nobiletin directly inhibits the ATP-binding cassette proteins P-glycoprotein and breast cancer resistance protein.
References Shen, C., et al.: J. Nutr. Biochem. 23, 1367 (2012); Pick, A., et al.: Bioorg. Med. Chem., 19, 2090 (2011); Wang, E., et al.: Chem. Res. Toxicol., 14, 1596 (2001)

• Marca: TRC

Propiedades químicas

• Peso molecular: 402.39
• Fórmula: C₂₁H₂₂O₈
• Color/Forma: Neat
• InChI: InChI=1S/C21H22O8/c1-23-13-8-7-11(9-15(13)24-2)14-10-12(22)16-17(25-3)19(26-4)21(28-6)20(27-5)18(16)29-14/h7-10H,1-6H3
• Clave InChI: InChIKey=MRIAQLRQZPPODS-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2)cc1OC