Oseltamivir EP Impurity E Glucose Adduct

Ref. TR-O701135

Información del producto

• Nombre: Oseltamivir EP Impurity E Glucose Adduct
• Sinónimos: (3R,4R)-Methyl 4-Acetamido-3-(pentan-3-yloxy)-5-(((3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)amino)cyclohex-1-enecarboxylate

Descripción

Applications Oseltamivir EP Impurity E Glucose Adduct is a byproduct in the synthesis of Oseltamivir Glucose Adduct 1 (O701035), which is derived from Oseltamivir Phosphate (O701000), which is an orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite (an antiviral drug). It is a COVID19-related research product.
References Oliyai, R., et al.: Pharm. Res., 15, 1300 (1998), Kim, C.U., et al.: Med. Chem. Res., 8, 392 (1998), Hayden, F.G., et al.: N. Engl. J. Med., 341, 1336 (1999), Treanor, J.J., et al.: J. Am. Med. Assoc., 283, 1016 (2000)

• Marca: TRC

Propiedades químicas

• Peso molecular: 460.52
• Fórmula: C₂₁H₃₆N₂O₉
• Color/Forma: Neat
• InChI: InChI=1S/C21H36N2O9/c1-5-12(6-2)31-14-8-11(21(29)30-4)7-13(16(14)22-10(3)25)23-20-19(28)18(27)17(26)15(9-24)32-20/h8,12-20,23-24,26-28H,5-7,9H2,1-4H3,(H,22,25)/t13?,14-,15+,16-,17+,18-,19+,20?/m1/s1
• Clave InChI: InChIKey=QTNIVDADXXJRDU-DLLQQZMTSA-N
• SMILES: CCC(CC)O[C@@H]1C=C(C(=O)OC)CC(NC2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H]1NC(C)=O