(S,S)-Oxaliplatin

CAS: 61758-77-8

Ref. TR-O845080

Información del producto

• Nombre: (S,S)-Oxaliplatin
• Sinónimos: Platinum, [(1S,2S)-1,2-cyclohexanediamine-kappaN1,kappaN2][ethanedioato(2-)-kappaO1,kappaO2]-, (SP-4-2)-, Platinum, (1,2-cyclohexanediamine-kappaN,kappaN')[ethanedioato(2-)-kappaO1,kappaO2]-, [SP-4-2-[1S-(trans)]]-, Platinum, [(1S,2S)-1,2-cyclohexanediamine-kappaN,kappaN'][ethanedioato(2-)-kappaO1,kappaO2]- (9CI), 1,2-Cyclohexanediamine, platinum complex, (1S-trans)-, [(1S,2S)-1,2-Cyclohexanediamine-kappaN1,kappaN2][ethanedioato(2-)-kappaO1,kappaO2]platinum, NSC 266042, Platinum, (1,2-cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']-, [SP-4-2-(1S-trans)]-, (SP-4-2)-[(1S,2S)-Cyclohexane-1,2-diamine-kappaN,kappaN'][ethanedioato(2-)-kappaO1,kappaO2]platinum, Oxaliplatin Imp. D (EP), Oxaliplatin Related Compound D (USP)

Descripción

Applications The (S,S) Oxaliplatin isomer. Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
References Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),

• Marca: TRC

Propiedades químicas

• Peso molecular: 397.29
• Fórmula: C₈H₁₄N₂O₄Pt
• Color/Forma: White
• InChI: (H,3,4)(H,5,6), InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8, 3-1(4)2(5)6, , /m0../s1, /q, , /h5-6H,1-4,7-8H2, +2/p-2/t5-,6-
• Clave InChI: InChIKey=ZROHGHOFXNOHSO-USPAICOZSA-L