Parecoxib

CAS: 198470-84-7

Ref. TR-P193245

Información del producto

• Nombre: Parecoxib
• Sinónimos: Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-, N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]propanamide, SC 69124, Valus-P, Vorth-P, Dynastat, N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide, N-[4-(5-methyl-3-phenyl-oxazol-4-yl)phenyl]sulfonylpropanamide, N-{[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonyl}propanamide, Parecoxib [USAN:INN:BAN], Propanamide, N-((4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)-, Sc 69124, Unii-9Tuw81Y3Ce, Xapit
• CAS: 198470-84-7

Descripción

Applications Parecoxib is used in the combination with Telmisartan for the treatment of endometriosis. Parecoxib reduces hippocampal inflammation and improve short-term memory function through the inhibition of COX-2 expression in aged rats after splenectomy.
References Nenicu, A.,et al.: Br. J. Pharmacol., 174, 2623 (2017); Li, P., et al.: Zhongnan Daxue Xuebao, Yixueban, 41, 586 (2016)

• Marca: TRC

Propiedades químicas

• Peso molecular: 370.42
• Fórmula: C₁₉H₁₈N₂O₄S
• Color/Forma: White to Off-White Solid
• InChI: InChI=1S/C19H18N2O4S/c1-3-17(22)21-26(23,24)16-11-9-14(10-12-16)18-13(2)25-20-19(18)15-7-5-4-6-8-15/h4-12H,3H2,1-2H3,(H,21,22)
• Clave InChI: InChIKey=TZRHLKRLEZJVIJ-UHFFFAOYSA-N
• SMILES: CCC(=O)NS(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2C)cc1