5-(1-Piperazinyl)-2-benzofurancarboxylic Acid Ethyl Ester Hydrochloride

CAS: 765935-67-9

Ref. TR-P480630

Información del producto

• Nombre: 5-(1-Piperazinyl)-2-benzofurancarboxylic Acid Ethyl Ester Hydrochloride
• Sinónimos: ethyl 5-piperazin-1-yl-1-benzofuran-2-carboxylate;hydrochloride
• Marca: TRC

Descripción

Applications 5-(1-Piperazinyl)-2-benzofurancarboxylic Acid Ethyl Ester Hydrochloride is an intermediate in the synthesis of Vilazodone (V265000), a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.
References Hu, B., et al.: Org. Proc. Res. Develop., 16, 1552 (2012); Heinrich, T., et al.: J. Med. Chem., 47, 4684 (2004);

Propiedades químicas

• Peso molecular: 310.78
• Fórmula: C₁₅H₁₉ClN₂O₃
• Color/Forma: Neat
• InChI: InChI=1S/C15H18N2O3.ClH/c1-2-19-15(18)14-10-11-9-12(3-4-13(11)20-14)17-7-5-16-6-8-17;/h3-4,9-10,16H,2,5-8H2,1H3;1H
• Clave InChI: InChIKey=IQUHEEPSXHVIPO-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cc2cc(N3CCNCC3)ccc2o1.Cl