Prucalopride Succinate

CAS: 179474-85-2

Ref. TR-P838950

Información del producto

• Nombre: Prucalopride Succinate
• Sinónimos: Butanedioic acid, compd. with 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (1:1), 7-Benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-, butanedioate (1:1) (9CI), R 108512, Resolor, Resotran, Prucalopride INTERMEDIATES, Prucalopride succinate
• CAS: 179474-85-2

Descripción

Applications Prucalopride is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

• Marca: TRC

Propiedades químicas

• Peso molecular: 485.96
• Fórmula: C₁₈H₂₆N₃O₃Cl•CH₆O₄
• Color/Forma: White to Pale Brown Solid
• InChI: 5-3(6)1-2-4(7)8/h11-12H,2-10,20H2,1H3,(H,21,23), InChI=1S/C18H26ClN3O3.C4H6O4/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14, 1-2H2,(H,5,6)(H,7,8)
• Clave InChI: InChIKey=QZRSNVSQLGRAID-UHFFFAOYSA-N
• SMILES: COCCCN1CCC(NC(=O)c2cc(Cl)c(N)c3c2OCC3)CC1.O=C(O)CCC(=O)O