5H-Pyrido[1,2,3-de]-1,4-benzoxazine-D3 Boron Derivative

CAS: 87531-64-4

Ref. TR-P875310

Información del producto

• Nombre: 5H-Pyrido[1,2,3-de]-1,4-benzoxazine-D3 Boron Derivative
• Sinónimos: (R)-2,11,11-Trifluoro-6-methyl-3-(4-methyl-D3-piperazin-1-yl)-9-oxo-5,6,9,11-tetrahydro-[1,3,2]dioxaborinino[5,4-c][1,4]oxazino[2,3,4-ij]quinolin-12-ium-11-uide
• Marca: TRC
• Descripción: Applications 5H-Pyrido[1,2,3-de]-1,4-benzoxazine-D3 Boron Derivative is an intermediate in the synthesis of (R)-Ofloxacin-d3 (O245742), which is a labelled fluorinated quinolone antibacterial. An enantiomer of Levofloxacin (L360000).References Hwangbo, H.J. et al.: Eur. J. Pharmac. Sci., 18, 197 (203); Gascon, A.R. et al.: J. Clin. Pharmacol, 40, 869 (2000); Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)

Propiedades químicas

• Peso molecular: 412.186
• Fórmula: C₁₈D₃H₁₆BF₃N₃O₄
• Color/Forma: Neat
• InChI: InChI=1S/C18H19BF3N3O4/c1-10-9-27-17-14-11(7-13(20)15(17)24-5-3-23(2)4-6-24)16-12(8-25(10)14)18(26)29-19(21,22)28-16/h7-8,10H,3-6,9H2,1-2H3/t10-/m1/s1/i2D3