Rabeprazole-D4 Sulfide

CAS: 117977-21-6

Ref. TR-R070511

Información del producto

• Nombre: Rabeprazole-D4 Sulfide
• Sinónimos: 2-(((4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole-D4, 1H-Benzimidazole,2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-, 2-(((4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole, 2-[((4-(3-Methoxypropoxy)-3-methylpyridine-2-yl)methyl)thio]-1H-benzimidazole, 2-[[4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfanyl]-1H-benzimidazole, 2-[[[3-Methyl-4-(3-methoxypropoxy)-2-pyridyl]methyl]thio]-1H-benzimidazole, 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole, 2-{[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl]methylthio}-1H-benzimidazole, H 295/43, Rabeprazole-thioether
• CAS: 117977-21-6

Descripción

Applications Rabeprazole-D4 Sulfide is an intermediate in the synthesis of Rabeprazole-d4 (R070492). Rabeprazole-D4 Sulfide is an isotope-labeled analogue of Rabeprazole Sulfide (Rabeprazole EP Impurity B), which is a metabolite of Rabeprazole (R070500).
References Morii, M., and Takeguchi, N.: J. Biol. Chem., 268, 21553 (1993); Yasuda, S., et al.: Int. J. Clin. Pharmacol. Ther., 32, 466 (1994); Cloud, M.L., et al.: Dig. Dis. Sci., 43, 993 (1998)

• Marca: TRC

Propiedades químicas

• Peso molecular: 347.468
• Fórmula: C₁₈D₄H₁₇N₃O₂S
• Color/Forma: Neat
• InChI: InChI=1S/C18H21N3O2S/c1-13-16(19-9-8-17(13)23-11-5-10-22-2)12-24-18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21)/i3D,4D,6D,7D
• Clave InChI: InChIKey=BSXAHDOWMOSVAP-ZDPIWEEJSA-N
• SMILES: [2H]c1c([2H])c([2H])c2[nH]c(SCc3nccc(OCCCOC)c3C)nc2c1[2H]