Ripasudil Hydrochloride

CAS: 934400-38-1

Ref. TR-R517900

Información del producto

• Nombre: Ripasudil Hydrochloride
• Sinónimos: Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-, hydrochloride (1:2), (S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride, 4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline dihydrochloride, Ripasudil dihydrochloride, (2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine dihydrochloride
• CAS: 934400-38-1

Descripción

Stability Hygroscopic
Applications Ripasudil Hydrochloride Dihydrate is a derivative of fasudil and a rho kinase inhibitor (1,2). It is used for the treatment of glaucoma and ocular hypertension.
References (1) Inazaki, H., et al.: J Glaucoma. (2016) (2) Isobe, T., et al.: J Ocul Pharmacol Ther. 32, 405 (2016)

• Marca: TRC

Propiedades químicas

• Peso molecular: 323.39 + x(36.46)
• Fórmula: C₁₅H₁₈FN₃O₂S•xHCl
• Color/Forma: Neat
• InChI: InChI=1S/C15H18FN3O2S.2ClH/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14;;/h2,4-5,9-11,17H,3,6-8H2,1H3;2*1H/t11-;;/m0../s1
• Clave InChI: InChIKey=CMDJNMACGABCKQ-XVSRHIFFSA-N
• SMILES: C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(F)c12.Cl.O.O