SB 431542

CAS: 301836-41-9

Ref. TR-S154660

Información del producto

• Nombre: SB 431542
• Sinónimos: 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide, 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide, Benzamide, 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-, Sb 431412, Sb-431542, Sb431542
• CAS: 301836-41-9

Descripción

Applications SB 431542 is a known Src family kinase inhibitor that effectively blocks the transforming growth factor-β1-induced cell migration and invasion in both established and primary carcinoma cells. Potent TGF-beta inhibitor.
References Tobias, B., et al.: Cancer. Chemother. Pharmacol., 70, 221 (2012); James, J., et al.: Molec. Cancer. Therap., 11, 930 (2012);

• Marca: TRC

Propiedades químicas

• Peso molecular: 384.39
• Fórmula: C₂₂H₁₆N₄O₃
• Color/Forma: Neat
• InChI: InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
• Clave InChI: InChIKey=FHYUGAJXYORMHI-UHFFFAOYSA-N
• SMILES: NC(=O)c1ccc(-c2nc(-c3ccc4c(c3)OCO4)c(-c3ccccn3)[nH]2)cc1