Selexipag

CAS: 475086-01-2

Ref. TR-S253150

Información del producto

• Nombre: Selexipag
• Sinónimos: 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide, 2-[4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy]-N-(methylsulfonyl)acetamide, ACT 293987, NS 304, Uptravi, 2-[4-[(5,6-Diphenylpyrazin-2-yl)-propan-2-ylamino]butoxy]-N-methylsulfonylacetamide, Acetamide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)-, Acetamide, 2-[4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)-, Act 293987, Ns 304
• CAS: 475086-01-2

Descripción

Applications Selexipag is an orally available, highly selective, long-acting prostacyclin (IP) receptor agonist prodrug. It is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.
References Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);

• Marca: TRC

Propiedades químicas

• Peso molecular: 496.62
• Fórmula: C₂₆H₃₂N₄O₄S
• Color/Forma: Light Yellow
• InChI: InChI=1S/C26H32N4O4S/c1-20(2)30(16-10-11-17-34-19-24(31)29-35(3,32)33)23-18-27-25(21-12-6-4-7-13-21)26(28-23)22-14-8-5-9-15-22/h4-9,12-15,18,20H,10-11,16-17,19H2,1-3H3,(H,29,31)
• Clave InChI: InChIKey=QXWZQTURMXZVHJ-UHFFFAOYSA-N
• SMILES: CC(C)N(CCCCOCC(=O)NS(C)(=O)=O)c1cnc(-c2ccccc2)c(-c2ccccc2)n1