Sulindac Sulfone-d6

CAS: 59973-80-7

Ref. TR-S699227

Información del producto

• Nombre: Sulindac Sulfone-d6
• Sinónimos: (Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid-d6, Aptosyn-d6, Exisulind-d6, FGN 1-d6, Prevatec-d6, (1Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (1Z)-, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (Z)-, Aposulind, Aptosyn, Exisulind, Fgn-1, Prevatac(former Brand Name), Prevatec, Sulindac sulfone, cis-5-Fluoro-2-methyl-1-[p-methylsulfonylbenzylidenyl]indene-3-acetic acid

Descripción

Applications Labelled analogue of Sulindac Sulfone, an active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis.
References Piazza, G.A. et al.: Cancer Res., 55, 3310 (1995);

• Marca: TRC

Propiedades químicas

• Peso molecular: 378.45
• Fórmula: C₂₀H₁₁D₆FO₄S
• Color/Forma: Neat
• InChI: InChI=1S/C20H17FO4S/c1-12-17(9-13-3-6-15(7-4-13)26(2,24)25)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-/i2D3,9D,11D2
• Clave InChI: InChIKey=MVGSNCBCUWPVDA-NUJVTHJYSA-N
• SMILES: [2H]/C(=C1\C(C)=C(C([2H])([2H])C(=O)O)c2cc(F)ccc21)c1ccc(S(=O)(=O)C([2H])([2H])[2H])cc1