Taurochenodeoxycholic Acid-d5 Sodium Salt

CAS: 6009-98-9

Ref. TR-T008133

Información del producto

• Nombre: Taurochenodeoxycholic Acid-d5 Sodium Salt
• Sinónimos: 2-[[(3a,5ß,7a)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid-d5 Sodium Salt, N-(3a,7a-dihydroxy-5ß-cholan-24-oyl)taurine-d5 Sodium Salt, 12-Deoxycholyltaurine-d5 Sodium Salt, 12-Desoxycholyltaurine-d5 Sodium Salt, 3a,7a-Dihydroxy-N-(2-sulfoethyl)-5ß-cholan-24-amide-d5 Sodium Salt, Chenodeoxycholyltaurine-d5 Sodium Salt, Chenyltaurine-d5 Sodium Salt, Taurochenodesoxycholic Acid Sodium Salt, Sodium taurochenodeoxycholate, Sodium 2-[(3,7-Dihydroxy-24-Oxocholan-24-Yl)Amino]Ethanesulfonate, Ethanesulfonic Acid, 2-[[(3Alpha,5Beta,7Alpha)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino]-, Monosodium Salt

Descripción

Stability Hygroscopic
Applications Taurochenodeoxycholic Acid-d5 (Major) Sodium Salt is the labelled analogue of Taurochenodeoxycholic Acid (T008130), a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.
References Emerman, S. et al.: J. Biol. Chem., 242, 661 (1967); Takikawa, Y. et al.: Falk Symp., 120, 249 (2001); Li, P. et al.: Zhong. Shour. Xue., 28, 1317 (2008)

• Marca: TRC

Propiedades químicas

• Peso molecular: 526.72
• Fórmula: C₂₆H₃₉D₅NNaO₆S
• Color/Forma: White To Beige
• InChI: InChI=1S/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17+,18-,19-,20+,21+,22-,24+,25+,26-;/m1./s1/i8D2,14D2,18D
• Clave InChI: InChIKey=IYPNVUSIMGAJFC-IYNWLQKKSA-M
• SMILES: [2H]C1([2H])C[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@H]4[C@H](C)CCC(=O)NCCS(=O)(=O)O[Na])[C@@H]3[C@H](O)C[C@@H]2C([2H])([2H])[C@]1([2H])O