2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone

CAS: 32384-65-9

Ref. TR-T279540

Información del producto

• Nombre: 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone
• Sinónimos: (3R,4S,5R,6R)-3,4,5-Tri[(trimethylsilyl)oxy]-6-[[(Trimethylsilyl)oxy]methyl]tetrahydro-2H-pyran-2-one
• Marca: TRC

Descripción

Applications 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone is an antidiabetic agent and an intermediate of Dapagliflozin (D185370). 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone acts as a reagent in the synthesis of trans-cyclohexane-bearing C-glucose as sodium glucose co-transporter 2 inhibitors.
References Shao, H., et al.: Youji Huaxue, 31, 836 (2011);

Propiedades químicas

• Peso molecular: 466.86
• Fórmula: C₁₈H₄₂O₆Si₄
• Color/Forma: Neat
• InChI: InChI=1S/C18H42O6Si4/c1-25(2,3)20-13-14-15(22-26(4,5)6)16(23-27(7,8)9)17(18(19)21-14)24-28(10,11)12/h14-17H,13H2,1-12H3/t14-,15-,16+,17-/m1/s1
• Clave InChI: InChIKey=VNGTZLYNGGLPIZ-FRBBGCKASA-N
• SMILES: C[Si](C)(C)OC[C@H]1OC(=O)[C@H](O[Si](C)(C)C)C(O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C