Tetrahydrocortisol

CAS: 53-02-1

Ref. TR-T293370

Información del producto

• Nombre: Tetrahydrocortisol
• Sinónimos: 2-hydroxy-1-[(3R,5R,8S,9S,10S,11S,13S,14S,17R)-3,11,17-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone, (3Alpha,5Beta,11Beta)-3,11,17,21-Tetrahydroxypregnan-20-One, (3α,5β,11β)-3,11,17,21-Tetrahydroxypregnan-20-one, 3-alpha,11-beta,17,21-Tetrahydroxy-5-beta-pregnan-20-one, 3alpha,11beta,17,21-Tetrahydroxy-5beta-pregnan-20-one, 3alpha,11beta,17,21-Tetrahydroxypregnan-20-one, 3alpha,5beta-Tetrahydrocortisol, 3α,11β,17,21-Tetrahydroxy-5β-pregnan-20-one, 3α,11β,17,21-Tetrol-5β-pregnan-20-one, 3α,11β,17α,21-Tetrahydroxy-5β-pregnan-20-one, 5-beta-Pregnan-20-one, 3-alpha,11-beta,17,21-tetrahydroxy-, 5-beta-Tetrahydrocortisol, 5beta-Pregnan-20-one, 3alpha,11beta,17,21-tetrahydroxy- (8CI), 5beta-Tetrahydrocortisol, 5β-Pregnan-20-one, 3α,11β,17,21-tetrahydroxy-, 5β-Tetrahydrocortisol, Ba 2682, Cortisol, tetrahydro-, Nsc 57431, Pregnan-20-one, 3,11,17,21-tetrahydroxy-, (3alpha,5beta,11beta)- (9CI), Pregnan-20-one, 3,11,17,21-tetrahydroxy-, (3α,5β,11β)-, THF (hormone), Tetrahydro F, Tetrahydrocompound F, Tetrahydrohydrocortisone, Urocortisol, 5β-Pregnane-3α,11β,17α,21-tetrol-20-one

Descripción

Applications Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer.
References Kodama, M., et. al.: J. Natl. Cancer I., 54, 1275 (1975); Klein, A., et. al.: Metabolism, 27, 731 (1978)

• Marca: TRC

Propiedades químicas

• Peso molecular: 366.49
• Fórmula: C₂₁H₃₄O₅
• Color/Forma: Off-White
• InChI: InChI=1S/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-16,18,22-24,26H,3-11H2,1-2H3/t12-,13-,14+,15+,16+,18-,19+,20+,21+/m1/s1
• Clave InChI: InChIKey=AODPIQQILQLWGS-GXBDJPPSSA-N
• SMILES: C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO