Información del producto
- 8-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione Hydrochloride
- BMY 13859
- BMY 13859-1
- MJ 13859-1
- Tiaspirone Hydrochloride
- 8-Azaspiro[4.5]decane-7,9-dione, 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-, hydrochloride (1:1)
- 8-Azaspiro[4.5]decane-7,9-dione, 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-, monohydrochloride
- 8-{4-[4-(1,2-Benzothiazol-3-Yl)Piperazin-1-Yl]Butyl}-8-Azaspiro[4.5]Decane-1,4-Dione Hydrochloride (1:1)
- 8-{4-[4-(1,2-Benzothiazol-3-Yl)Piperazin-1-Yl]Butyl}-8-Azaspiro[4.5]Decane-7,9-Dione Hydrochloride (1:1)
- Bmy 13859-1
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- Bmy-13859
- MJ-13859(free base)
- Mj 13859-1
- Mj-138591
- Tiaspirone hydrochloride
- Tiospirone hydrochloride
Applications Tiospirone is an atypical antipsychotic agent and used in the treatment of schizophrenia (1,2,3,). Tiospirone acts as a 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2C, and 5-HT7 receptor inverse agonist, and D2, D4, and α1-adrenergic receptor antagonist.
References (1) Rauly-Lestienne, I. et al.: Naun. Schmeid. Arch. Pharmacol., 376, 93 (2007) (2) Weiner, D.M. et al.: J. Pharmacol. Exp. Therap., 299, 268 (2001) (3) White, F.J. et al.: Neuropharmacology, 25, 995 (1986)