Tipiracil Hydrochloride

CAS: 183204-72-0

Ref. TR-T444890

Información del producto

• Nombre: Tipiracil Hydrochloride
• Sinónimos: 5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione Monohydrochloride, TAS 1-462, TPI Hydrochloride, 2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, hydrochloride (1:1), 2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, monohydrochloride, 5-Chloro-6-(2-iminopyrrolidin-1-ylmethyl)uracil hydrochloride, 5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione monohydrochloride, 5-Chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione hydrochloride, TPI hydrochloride, Tas 1-462, Tipiracil, Tipiracil HCl, Tipiracil hydrochloride

Descripción

Applications Tipiracil Hydrochloride serves as a treatment for metastatic colorectal cancer (mCRC). A thymidine phosphorylase inhibitor.
References Sugita, K., et al.: Oncol., 91, 224-230 (2016); van der Velden, D. L., et al.: Clin. Cancer Res., 22, 2835-2839 (2016)

• Marca: TRC

Propiedades químicas

• Peso molecular: 242.66 + (36.46)
• Fórmula: C₉H₁₁ClN₄O₂·(HCl)
• Color/Forma: White To Off-White
• InChI: InChI=1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H
• Clave InChI: InChIKey=KGHYQYACJRXCAT-UHFFFAOYSA-N
• SMILES: Cl.N=C1CCCN1Cc1nc(O)nc(O)c1Cl