Tofacitinib Impurity Z

CAS: 477600-76-3

Ref. TR-T528030

Información del producto

• Nombre: Tofacitinib Impurity Z
• Sinónimos: 1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one,1-[(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]ethanone

Descripción

Impurity Tofacintinib Impurity
Applications Tofacitinib Impurity Z is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3 (Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
References Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)

• Marca: TRC

Propiedades químicas

• Peso molecular: 287.36
• Fórmula: C₁₅H₂₁N₅O
• Color/Forma: White Solid
• InChI: InChI=1S/C15H21N5O/c1-10-5-7-20(11(2)21)8-13(10)19(3)15-12-4-6-16-14(12)17-9-18-15/h4,6,9-10,13H,5,7-8H2,1-3H3,(H,16,17,18)/t10-,13+/m1/s1
• Clave InChI: InChIKey=FJIVGKFVGCGMFC-MFKMUULPSA-N
• SMILES: CC(=O)N1CC[C@@H](C)[C@@H](N(C)c2ncnc3[nH]ccc23)C1