Tolimidone

CAS: 41964-07-2

Ref. TR-T535340

Información del producto

• Nombre: Tolimidone
• Sinónimos: 5-(3-methylphenoxy)-1H-pyrimidin-2-one, 2(1H)-Pyrimidinone, 5-(3-methylphenoxy)-, 5-(3-Methylphenoxy)-2(1H)-pyrimidinone, 5-(3-methylphenoxy)pyrimidin-2(1H)-one, 5-(m-Tolyloxy)-2(1H)-pyrimidinone, Cp 26154, Mlr 1023, NSC 314335, Unii-Mu3Jd8E9Is

Descripción

Applications Tolimidone (MLR-1023) is an allosteric Lyn kinase activator that has been shown to reduce blood glucose levels in mice. Studies show that Tolimidone is an effective insulin receptor-potentiating agent that is potentially capable of producing durable blood glucose-lowering activity in diabetics. Tolimidone is a candidate for the treatment of type 2 diabetes.
References Ochman, A.R. et al.: J. Pharmacol. Exp. Ther., 342, 23 (2012); Saporito, M.S. et al.: J. Pharmacol. Exp. Ther., 342, 15 (2012);

• Marca: TRC

Propiedades químicas

• Peso molecular: 202.209
• Fórmula: C₁₁H₁₀N₂O₂
• Color/Forma: Neat
• InChI: InChI=1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14)
• Clave InChI: InChIKey=HJQILFPVRNHTIG-UHFFFAOYSA-N
• SMILES: Cc1cccc(Oc2cnc(O)nc2)c1