Tolvaptan-d7

CAS: 1246818-18-7

Ref. TR-T536652

Información del producto

• Nombre: Tolvaptan-d7
• Sinónimos: N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide-d7, OPC 41061-d7
• CAS: 1246818-18-7

Descripción

Applications Labelled Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000), Udelson, J., et al.: Circulation, 104, 2417 (2001), Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005), Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006),

• Marca: TRC

Propiedades químicas

• Peso molecular: 455.98
• Fórmula: C₂₆H₁₈D₇ClN₂O₃
• Color/Forma: Neat
• InChI: InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)/i1D3,3D,4D,6D,7D
• Clave InChI: InChIKey=GYHCTFXIZSNGJT-FFQSSJIFSA-N
• SMILES: [2H]c1c([2H])c([2H])c(C([2H])([2H])[2H])c(C(=O)Nc2ccc(C(=O)N3CCCC(O)c4cc(Cl)ccc43)c(C)c2)c1[2H]