Treprostinil Diolamine

CAS: 830354-48-8

Ref. TR-T719525

Información del producto

• Nombre: Treprostinil Diolamine
• Sinónimos: Treprostinil diethanolamine, UT 15C, 2,2'-Azanediyldiethanol 2-(((1R,2R,3aS,9aS)-2-hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetate

Descripción

Applications Treprostinil Diolamine is a sustained-release oral formulation of Treprostinil (T719500) and was studied to determine whether it could provide a more convenient prostacyclin treatment option for patients with less severe pulmonary arterial hypertension.Treprostinil Diolamine is an sustained-release oral prostacyclin analog and was studied to determine pharmacokinetic profile in PAH patients after chronic dosing,
References Tapson, Victor F., Chest, 144, 952-958, (2013)White, R. James., Journal of Cardiovascular Pharmacology, 61, 474-481, (2013)

• Marca: TRC

Propiedades químicas

• Peso molecular: 495.649
• Fórmula: C₂₃H₃₄O₅·C₄H₁₁NO₂
• Color/Forma: Neat
• InChI: InChI=1S/C23H34O5.C4H11NO2/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25;6-3-1-5-2-4-7/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27);5-7H,1-4H2/t16-,17-,18+,19-,21+;/m0./s1
• Clave InChI: InChIKey=RHWRWEUCEXUUAV-ZSESPEEFSA-N
• SMILES: CCCCC[C@H](O)CC[C@@H]1[C@H]2Cc3cccc(OCC(=O)O)c3C[C@H]2C[C@H]1O.OCCNCCO