3,3’,5-Triiodo-L-thyronine Methyl Ester Trifluoroacetamide

CAS: 3006-04-0

Ref. TR-T795403

Información del producto

• Nombre: 3,3’,5-Triiodo-L-thyronine Methyl Ester Trifluoroacetamide
• Sinónimos: (S)-Methyl 3-(4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-2-(2,2,2-trifluoroacetamido)propanoate, L-3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-N-(trifluoroacetyl)-alanine Methyl Ester
• CAS: 3006-04-0

Descripción

Applications 3,3’,5-Triiodo-L-thyronine Methyl Ester Trifluoroacetamide is an intermediate in synthesizing 3,3’,5-Triiodo-L-thyronine O-β-D-Glucuronide (T795405), a O-glucuronide derivative of 3,3’,5-Triiodo-L-thyronine (T795380); one of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
References Gross, J., et al.: Lancet I, 439 (1952); Roche, J., et al.: Biochim. Biophys. Acta, 11, 215 (1953); Chacon, M.A., et al.: J. Pediatr., 99, 758 (1981); Chopra, I.J., et al.: Thyroid, 6, 255 (1996)

• Marca: TRC

Propiedades químicas

• Peso molecular: 761.008
• Fórmula: C₁₈H₁₃F₃I₃NO₅
• Color/Forma: Yellow Solid
• InChI: InChI=1S/C18H13F3I3NO5/c1-29-16(27)13(25-17(28)18(19,20)21)6-8-4-11(23)15(12(24)5-8)30-9-2-3-14(26)10(22)7-9/h2-5,7,13,26H,6H2,1H3,(H,25,28)/t13-/m0/s1
• Clave InChI: InChIKey=SHCRKLCIFKMVGW-ZDUSSCGKSA-N
• SMILES: COC(=O)[C@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)NC(=O)C(F)(F)F