5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine

CAS: 30806-86-1

Ref. TR-T795855

Información del producto

• Nombre: 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine
• Sinónimos: Trimethoprim Imp. B (EP), Trimethoprim USP Related Compound B, Trimethoprim USP RC B, (2,4-Diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanone, 115U67, GW 382217X, BP Trimethoprim Impurity B, Ph Eur Trimethoprim Impurity B, Trimethoprim Related Compound B, Trimethoprim Impurity B, Ketone,2,4-diamino-5-pyrimidinyl 3,4,5-trimethoxyphenyl (8CI), Ro 20-0570/002
• CAS: 30806-86-1

Descripción

Stability Hygroscopic
Applications 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, is a derivative of Trimethoprim (T795615), an antibacterial agent. 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, is a possible potent and selective inhibitor targeting dihydrofolate reductase of C. hominis, used for the treatment of Cryptosporidiosis.
References Popov, V. M., et al.: Bioorg. Med. Chem. Lett., 16, 4366 (2006); Brogden, R.N., et al.: Drugs, 23, 405 (1982);

• Marca: TRC

Propiedades químicas

• Peso molecular: 304.30
• Fórmula: C₁₄H₁₆N₄O₄
• Color/Forma: Light Yellow Solid
• InChI: InChI=1S/C14H16N4O4/c1-20-9-4-7(5-10(21-2)12(9)22-3)11(19)8-6-17-14(16)18-13(8)15/h4-6H,1-3H3,(H4,15,16,17,18)
• Clave InChI: InChIKey=GAAPPIKAFNZRLA-UHFFFAOYSA-N
• SMILES: COc1cc(C(=O)c2cnc(N)nc2N)cc(OC)c1OC