(3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester

CAS: 157401-01-9

Ref. TR-T887910

Información del producto

• Nombre: (3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester

Descripción

Applications (3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester is an intermediate in the synthesis of (25R)-3β,7α,12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood.
References Schroepfer, G., et al.: Physiol. Rev., 80, 361 (2000); Bjorkhem, I.: J. Clin. Invest., 6, 725(2002); Bjorkhem, I., et al.: Arterio. hromb. Vascul. Biol., 22, 734 (2002)

• Marca: TRC

Propiedades químicas

• Peso molecular: 476.35
• Fórmula: C₂₉H₄₈O₅
• Color/Forma: Neat
• InChI: InChI=1S/C29H48O5/c1-6-34-27(33)18(3)9-7-8-17(2)21-10-11-22-26-23(16-25(32)29(21,22)5)28(4)13-12-20(30)14-19(28)15-24(26)31/h9,17,19-26,30-32H,6-8,10-16H2,1-5H3/b18-9+/t17-,19+,20-,21-,22?,23?,24-,25+,26?,28+,29-/m1/s1
• Clave InChI: InChIKey=RWMGPYRVBGIPEW-IZYHOLNDSA-N
• SMILES: CCOC(=O)/C(C)=C/CC[C@@H](C)[C@H]1CCC2C3C(C[C@H](O)[C@@]21C)[C@@]1(C)CC[C@@H](O)C[C@H]1C[C@H]3O