TRV-130 Hydrochloric Acid Salt

CAS: 1401031-39-7

Ref. TR-T895530

Información del producto

• Nombre: TRV-130 Hydrochloric Acid Salt
• Sinónimos: Oliceridine, (9R)-N-[(3-methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine, monohydrochloride, (9R)-N-[(3-Methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine hydrochloride (1:1), 6-Oxaspiro[4.5]decane-9-ethanamine, N-[(3-methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-, hydrochloride (1:1), (9R)-
• CAS: 1401031-39-7

Descripción

Applications TRV-130 is a μ-opioid receptor (MOR) G protein-biased ligand. It is potently analgesic while causing less gastrointestinal dysfunction and respiratory suppression than morphine at equianalgesic doses.
References DeWire, S., et al.: J. Pharm. Exper. Ther., 344, 708 (2013); Soergel, D., et al.: Pain, 155, 1829 (2014)

• Marca: TRC

Propiedades químicas

• Peso molecular: 423.01
• Fórmula: C₂₂H₃₁ClN₂O₂S
• Color/Forma: Neat
• InChI: InChI=1S/C22H30N2O2S.ClH/c1-25-18-7-15-27-19(18)16-23-13-10-21(20-6-2-5-12-24-20)11-14-26-22(17-21)8-3-4-9-22;/h2,5-7,12,15,23H,3-4,8-11,13-14,16-17H2,1H3;1H/t21-;/m1./s1
• Clave InChI: InChIKey=YIIWXYLJZRISQP-ZMBIFBSDSA-N
• SMILES: COc1ccsc1CNCC[C@@]1(c2ccccn2)CCOC2(CCCC2)C1.Cl