D-Valinol

CAS: 4276-09-9

Ref. TR-V094355

Información del producto

• Nombre: D-Valinol
• Sinónimos: D-2-Amino-3-methyl-1-butanol, (-)-2-Amino-3-methyl-1-butanol, (-)-Valinol, (2R)-2-Amino-3-methyl-1-butanol, (2R)-2-Amino-3-methylbutan-1-ol, (R)-(-)-2-Amino-3-methyl-1-butanol, (R)-2-Amino-3-methyl-1-butanol, (R)-2-Amino-3-methylbutan-2-ol, (R)-2-Amino-3-methylbutanol, (R)-Valinol, [(R)-1-(Hydroxymethyl)-2-methylpropyl]amine, (R)-(-)-2-Amino-3-methyl-1-butanol, (R)-2-amino-3-methylbutan-1-ol, 1-Butanol, 2-amino-3-methyl-, (2R)-, 1-Butanol, 2-amino-3-methyl-, (R)-, 1-Butanol, 2-amino-3-methyl-, <span class="text-smallcaps">D</span>-, <span class="text-smallcaps">D</span>-Valinol, D-valinol (R-2-amino-3-methyl-1-butanol)
• CAS: 4276-09-9

Descripción

Applications D-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer's disease.
References Radl, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2015, ahead of print); Fukunaga, K., et al.: Bioorg. Med. Chem. Lett., 25, 1086 (2015)

• Marca: TRC

Propiedades químicas

• Peso molecular: 103.16
• Fórmula: C₅H₁₃NO
• Color/Forma: Off-White Low-Melting Solid
• InChI: InChI=1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3
• Clave InChI: InChIKey=NWYYWIJOWOLJNR-UHFFFAOYSA-N
• SMILES: CC(C)[C@@H](N)CO