Vildagliptin Cyclo Imidamide

CAS: 1789703-37-2

Ref. TR-V305010

Información del producto

• Nombre: Vildagliptin Cyclo Imidamide
• Sinónimos: Pyrrolo[1,2-a]pyrazin-4(1H)-one, hexahydro-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-1-imino-, Hexahydro-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-1-iminopyrrolo[1,2-a]pyrazin-4(1H)-one, 1-Amino-2-(3-hydroxyadamantan-1-yl)-3,6,7,8-tetrahydropyrrolo[1,2-a]pyrazin-4-one

Descripción

Applications Vildagliptin Cyclo Imidamide Hydrochloride is an impurity of vildagliptin (V305000). Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. ASide from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

• Marca: TRC

Propiedades químicas

• Peso molecular: 303.40
• Fórmula: C₁₇H₂₅N₃O₂
• Color/Forma: Neat
• InChI: InChI=1S/C17H25N3O2/c18-15-13-2-1-3-19(13)14(21)9-20(15)16-5-11-4-12(6-16)8-17(22,7-11)10-16/h11-12,22H,1-10,18H2
• Clave InChI: InChIKey=ZZYCWDSBZNHPIN-BQEHCZBJSA-N
• SMILES: N=C1C2CCCN2C(=O)CN1[C@@]12C[C@@H]3C[C@@H](C[C@@](O)(C3)C1)C2