Zotarolimus, >90%

CAS: 221877-54-9

Ref. TR-Z700800

Información del producto

• Nombre: Zotarolimus, >90%
• Sinónimos: (42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin, 42-(1-Tetrazolyl)rapamycin, A 179578, ABT 578, Abt 578, Endeavor, Rapamycin, 42-deoxy-42-(1H-tetrazol-1-yl)-, (42S)-, Resolute, Unii-H4gxr80ize
• CAS: 221877-54-9

Descripción

Applications A tetrazole-containing Rapamycin analog as immunomodulator and useful in the treatment of restenosis and immune and autoimmune diseases.
References Moses, J., et al.: N. Engl. J. Med., 349, 1315 (2003), Ako, J., et al.: J. Am. Coll. Cardiol., 46, 1002 (2005), Wagner, et al.: Bioorg. Med. Chem. Lett., 15, 5340 (2005), Hong, M., et al.: Circulation, 113, 414 (2006),

• Marca: TRC

Propiedades químicas

• Peso molecular: 966.21
• Fórmula: C₅₂H₇₉N₅O₁₂
• Pureza: >90%
• Color/Forma: White to Pale Yellow Solid
• InChI: InChI=1S/C52H79N5O12/c1-31-16-12-11-13-17-32(2)43(65-8)28-39-21-19-37(7)52(64,69-39)49(61)50(62)56-23-15-14-18-41(56)51(63)68-44(34(4)26-38-20-22-40(45(27-38)66-9)57-30-53-54-55-57)29-42(58)33(3)25-36(6)47(60)48(67-10)46(59)35(5)24-31/h11-13,16-17,25,30-31,33-35,37-41,43-45,47-48,60,64H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,32-17+,36-25+/t31-,33-,34-,35-,37-,38+,39+,40+,41+,43+,44+,45-,47-,48+,52-/m1/s1
• Clave InChI: InChIKey=CGTADGCBEXYWNE-XZLPDJTBSA-N
• SMILES: CO[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@H](n3cnnn3)[C@H](OC)C2)CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C1C