Entre las marcas de nuestros más de 25 colaboradores destaca TargetMol
We have reached an agreement with TargetMol: CymitQuimica clients will benefit for a 20% discount on all TargetMol products until the end of the year.On our website you can find the products offered by this partner, which has become one of the world's most recognised compound libraries and small molecule inhibitors supplier. TargetMol offers approximately 120 compound libraries and a wide range of chemical products and kits for life sciences.
Termina el 31 dic( quedan 8 días )
GlcNAc-MurNAc
CAS:GlcNAc-MurNAc is a disaccharide and mild TLR4 agonist with a Kd of 383 μM for mouse TLR4. It directly binds to TLR4, activating the downstream NF-κB and IRF pathways. Additionally, GlcNAc-MurNAc ameliorates dextran sulfate sodium salt (DSS)-induced colitis in mice through a TLR4-dependent mechanism, making it useful for inflammatory bowel disease research.Fórmula:C19H32N2O13Forma y color:SolidPeso molecular:496.46VH032-cyclopropane-F-C4-CHO
VH032-cyclopropane-F-C4-CHO is an E3 ubiquitinase ligand-linker conjugate, which can be utilized in the synthesis of LC-MF-4.Forma y color:Odour SolidPexidartinib
CAS:<p>Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential</p>Fórmula:C20H15ClF3N5Pureza:98.34% - 99.45%Forma y color:SolidPeso molecular:417.81Trimethylene carbonate
CAS:Trimethylene carbonate is a bioactive chemical.Fórmula:C4H6O3Pureza:98%Forma y color:SolidPeso molecular:102.09ddTTPαS tetrasodium
ddTTPαS tetrasodium is a sulfur-containing nucleotide triphosphate derivative used in chain extension during PCR assays.Forma y color:Odour SolidAuristatin S
CAS:AuristatinS is a potent anti-tumor agent that serves as an Auristatin payload. It effectively reduces the bystander effect and decreases off-target toxicity. In the Karpas/KarpasBVR cell model, AuristatinS exhibits excellent tolerability. It can be used as the cytotoxic component in antibody-drug conjugates (ADCs) for treating various types of cancer.Fórmula:C38H65N5O8Forma y color:SolidPeso molecular:719.95AT-9283 L-lactate
CAS:<p>AT-9283 L-lactate is an inhibitor of aurora kinase.</p>Fórmula:C22H29N7O5Pureza:98%Forma y color:SolidPeso molecular:471.52Lck degrader-1
Lckdegrader-1 (Compound 17) is a molecular glue degrader that targets lymphocyte-specific protein tyrosine kinase (LCK) with a DC50 of 23.1 nM. It holds potential for research in T-cell acute lymphoblastic leukemia (T-ALL).Forma y color:Odour SolidAc-Phe-NH2
CAS:Ac-Phe-NH2 is a non-competitive inhibitor of polyubiquitin chain elongation at Ki value of 8 ± 1.2 mM.Fórmula:C11H14N2O2Pureza:99.9%Forma y color:SolidPeso molecular:206.24Clothianidin
CAS:Clothianidin (TI 435), an insecticide, stimulates nAChR as acetylcholine agonist, not AChE inhibitor.Fórmula:C6H8ClN5O2SPureza:99.71% - 99.87%Forma y color:Solid PowderPeso molecular:249.68PROTAC BRD4 Degrader-36
PROTACBRD4 Degrader-36 (Compound TrimTAC-1) is a BRD4 PROTAC degrader. It has a DC50 of 0.649 nM and a Dmax of 71% in PANC-1 cells. Additionally, PROTACBRD4 Degrader-36 exhibits cytotoxicity towards PANC-1 cells with a GI50 of 0.103 μM. This compound is applicable for tumor research.Forma y color:Odour SolidNPRA agonist-11
CAS:NPRA agonist-11 (Example 161) is an NPRA (NPR1) agonist with AC50 values of 1.681 μM and 0.989 μM for human and monkey, respectively. It is applicable in research on cardiovascular and other diseases.Fórmula:C37H52FN7O2Forma y color:SolidPeso molecular:645.85PROTAC BRD4 Degrader-38
PROTACBRD4 Degrader-38 is a BRD4 PROTAC degrader with DC50 values of 86 nM and 106 nM for the short and long BRD4 isoforms, respectively. It significantly induces BRD4 degradation through covalent binding at the C232 site of the E3 ligase TRIM28.Forma y color:Odour SolidddATP lithium
ddATP (lithium) (2',3'-Dideoxyadenosine 5'-triphosphate (lithium)) is an active metabolite of 2',3'-dideoxyinosine and acts as a chain extension inhibitor of DNA polymerase. It is employed in DNA sequencing using the Sanger method and is also used in studies related to viral infections.Forma y color:Odour SolidChlorfluazuron
CAS:Chlorfluazuron, a chitin synthesis inhibitor, is commonly used as an insect growth regulator for controlling the major insect pests in crops.Fórmula:C20H9Cl3F5N3O3Forma y color:White Crystals Or Crystalline PowderPeso molecular:540.66PZ671
PZ671 is a potent PROTAC degrader targeting Bcl-xL, exhibiting an IC50 of 1.3 nM in MOLT-4 cells and a DC50 of 0.9 nM for Bcl-xL. It induces apoptosis in MOLT-4 cells and effectively inhibits tumor growth in MOLT-4 xenograft mice, while quickly restoring transiently reduced platelet counts. PZ671 is applicable in cancer research, including studies on small cell lung cancer.Forma y color:Odour SolidJY-5
JY-5 is an E3 ligase ligand (E3 ligase Ligand) suitable for the synthesis of PROTAC JY-21.Forma y color:Odour SolidHK-2-IN-1
HK-2-IN-1 is an inhibitor of Hexokinase 2 (HK-2). It exhibits non-activation effects on human recombinant HK-2 enzyme. HK-2-IN-1 possesses antitumor activity, impacting immune cells within the tumor microenvironment. It has immunomodulatory properties and is applicable in research on cancers such as colon cancer, liver cancer, and breast cancer.Forma y color:Odour SolidMetoprolol acid
CAS:Metoprolol acid is a urinary metoprolol metabolite and doesn't work pharmacologically.Fórmula:C14H21NO4Pureza:98%Forma y color:SolidPeso molecular:267.33PROTAC HER2 degrader-1
CAS:PROTACHER2 degrader-1 is a highly selective HER2 PROTAC degrader with a DC50 of 69 nM and a Dmax of 96%. It effectively inhibits HER2-positive cell proliferation and tumor growth by inducing sustained HER2 degradation and strongly inhibiting downstream pathways (AKT and ERK). Additionally, PROTACHER2 degrader-1 can induce apoptosis in BT-474 cells and is useful for researching HER2-positive cancers.Fórmula:C49H55N11O7Forma y color:SolidPeso molecular:910.03
