Entre las marcas de nuestros más de 25 colaboradores destaca TargetMol

<p>Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide</p>

Pellitorine (Pellitorin) is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist.

MC12 is a thiazole derivative and an inhibitor of SARS-CoV-2 main protease (IC50: 77.7 nM). It effectively inhibits the main protease of both SARS-CoV and SARS-CoV-2, with low cytotoxicity and good stability. MC12 is suitable for research in anti-COVID-19 drug development.

sEH-IN-21 is an orally active inhibitor of sEH, exhibiting IC50 values of 0.1 nM for both hsEH and msEH. It significantly suppresses the NF-κB signaling pathway. sEH-IN-21 demonstrates potent anti-inflammatory activity by reducing IL-6 and TNF-α release and maintaining intestinal barrier integrity. It is applicable in research on inflammatory bowel disease (IBD).

<p>Dioctyl Decanedioate is commonly used as a plasticiser and is widely used in biochemical experiments and drug synthesis research.</p>

2'(3')-Br-ANT-GTP tetrasodium is a derivative of GTP. It can be excited at a wavelength of 350 nm and emits light in the range of 380-550 nm.

PROTACBRD4 ligand-4 is a BRD4 ligand used in the synthesis of [PROTACBRD4 Degrader-37].

Perfluorosebacic acid is a perfluoroalkanedicarboxylic acid, which is useful to prepare synthetic polymers.

Isodienestrol, a derivative of Diethylstilbestrol, acts as a microtubule (Microtubule) inhibitor. It is utilized in cancer research.

FHND5071 (1H) is a selective inhibitor of RET (rearranged during transfection) tyrosine kinase. It shows potential for research applications in RET-driven cancers, such as thyroid and lung cancer.

Benzene, 1,3-diphenoxy- is a bioactive chemical.

Yoda2 (KC289), the potassium salt of Yoda1, is an agonist of PIEZO1 with an EC50 of 150 nM. It induces Ca2+ elevation in HeLa cells and can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50= 1.2 μM). Additionally, Yoda2 is capable of stimulating NOS3 and promoting NO production.

<p>3-Ethylaniline is a bioactive chemical.</p>

PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.

3-Ethylphenol exhibits ciliate toxicity and inhibits Tetrahymena pyriformis, and is widely used in biochemical experiments and drug synthesis research.

SJ11646 is a Dasatinib-based LCK PROTAC degrader with a DC50 of 0.00838 pM. It exhibits potent cytotoxicity against LCK-activated T-cell acute lymphoblastic leukemia (T-ALL) cells and primary leukemia samples, significantly prolongs LCK signal inhibition, and induces apoptosis in T-ALL cells. SJ11646 binds with high affinity to 51 human kinases, particularly ABL1, KIT, and DDR1. In mouse models of T-ALL, SJ11646 demonstrates exceptional anti-leukemic efficacy.

TKL-IN-2 (Compound 7m) is a TKL inhibitor with an IC50 of 0.11 mg/L against SvTKL. It exhibits excellent herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus, while being safe for corn, wheat, soybean, and cotton. TKL-IN-2 is suitable for research in weed control in crop fields.

Elafibranor (GFT505) sulfoxide is a sulfoxide metabolite of Elafibranor, which acts as an agonist for PPARα/δ with EC50 values of 45 nM and 175 nM, respectively. Elafibranor is utilized in research related to primary biliary cholangitis.

Ocipumaltib (Example 2) is an inhibitor of mucosa-associated lymphoid tissue protein 1 (MALT1). It functions as an antineoplastic agent and is utilized in the study of cancer, infections, neurological disorders, and hematological diseases.

m-Ethoxybenzaldehyde is a bioactive chemical.