TM Biblioteca de compuestos

<p>A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening；</p>

<p>Diversity: Selected from 1,600,000 drug-like compounds covering rich chemical scaffolds, 5000 compounds representing 5000 scaffolds；</p>

<p>A unique collection of 246 fragment-like small molecules for FBDD;</p>

<p>A unique collection of 197 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of xnum pure natural products and their derivatives with known biological activity for drug discovery, pharmacological study, stem cell differentiation, fingerprint study and quality research, and can be used for high throughput screen</p>

<p>A unique collection of 3840 natural products for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 635 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of xnum natural alkaloids can be used for high throughput and high content screening；</p>

<p>A unique collection of 514 flavonoids can be used for high throughput and high content screening；</p>

<p>A unique collection of xnum natural terpenes and terpenoids can be used for high throughput and high content screening；</p>

<p>A unique collection of 362 saccharides and glycosides compounds can be used for HTS and HCS；</p>

<p>Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening.</p>

<p>A unique collection of xnum natural product monomers that meet the &amp;quot;Lipinski&amp;#039;s Rule of Five&amp;quot;, a powerful tool for HTS and HCS screening;</p>

<p>A unique collection of 420 natural flavor small molecules.</p>

<p>A collection of 221 natural product molecules originated from Yao medicine, which can be used for high-throughput and high-content screening.</p>

<p>A collection of 747 natural product molecules originated from Tibetan medicine, which can be used for high-throughput and high-content screening.</p>

<p>A collection of 950 natural product molecules originated from Mongolian medicine, which can be used for high-throughput and high-content screening.</p>

<p>A unique collection of xnum compounds featuring natural product molecules derived from Miao medicine that can be used for high-throughput and high-content</p>

<p>A unique collection of 1290 compounds from food as medicine for high throughput and high content screening;</p>

<p>A unique collection of 144 marine natural products for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 550 microbial natural products for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 219 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS);</p>

A unique collection of xnum species of natural products with anti-infective activity for high throughput screening (HTS) and high content screening (HCS);

<p>A unique collection of 253 natural products with antiparasitic activity, a powerful tool for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 1772 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A collection of xnum TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery</p>

<p>A unique collection of xnum monomers from 60 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening；</p>

<p>A collection of 268 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies.</p>

<p>A collection of 382 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies.</p>

<p>A unique collection of xnum compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.</p>

<p>xnum compounds derived from heat-clearing and detoxifying TCM for HCS and HTS.</p>

<p>A unique collection of xnum natural products included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study;</p>

<p>A unique collection of xnum compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in</p>

<p>A unique collection of xnum tobacco monomer compounds for high throughput screening and high content screening;</p>

<p>A collection of xnum compounds derived from traditional medicinal formulas, serving as a powerful tool in drug development, pharmacological research, and more.</p>

<p>A unique collection of 693 rare natural products, which can be used for high throughput screening (HTS) and high content screening (HCS);</p>

<p>The TargetMol Food Sourced Compound Library contains xnum compounds.</p>

<p>The Dietary Supplement Library from TargetMol contains xnum major ingredients of dietary supplements.</p>

<p>A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists &amp;amp;</p>

<p>A unique collection of 2247 anti-obesity compounds for high throughput and high content screening;</p>

<p>678 hypertension-related small molecules for high-throughput and high-content screening.</p>

<p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>

<p>A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;</p>

<p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>

<p>A unique collection of 144 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;</p>

<p>A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;</p>

<p>The TargetMol's High Solubility Fragment Library collects 2725 fragment-like small molecules meeting with strict Astex Rule of Three Criteria or fragment based drug discovery.</p>

Highly soluble multifunctional fragment library contains xnum kinds of fragment molecules.

<p>The compound library of highly soluble micro-fragments consists of 1081 low-molecular-weight fragments.</p>

<p>High Solubility Pharmacophore Fragment library contains xnum fragment small molecules.</p>

<p>The highly soluble halogenated fragment library contains 796 halogenated fragment compounds.</p>

<p>The library of highly soluble 3D structural diversity fragments contains xnum compounds.</p>

<p>369 compounds in total in the Highly Solubility Covalent Heterocyclic Fragment Library</p>

<p>To meet the high demand for novel and small carboxylic acid fragments for FBDD, we have carefully selected and created a library of 1806 soluble carboxylic acid fragments.</p>

<p>A unique collection of xnum osteogenesis related compounds for high throughput and high content screening;</p>

<p>A unique collection of xnum stem cell differentiation signaling targeted compounds for high throughput and high content screening;</p>

<p>A unique collection of xnum cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of xnum reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.</p>

<p>A unique collection of 3279 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of xnum compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of xnum compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；</p>

<p>A unique collection of xnum ubiquitination related small chemicals can be used for high throughput and high content screening；</p>

<p>A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；</p>

<p>TargetMol’s Cuproptosis Compound Library is a collection of xnum compounds related to copper-dependent death that can be used to study its mechanism and related</p>

<p>xnum types of active small molecules associated with pyroptosis for high-throughput and high-content screening.</p>

<p>1119 drug fragments，a must-have tool for FBDD;</p>

<p>A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;</p>

<p>425 food additives;</p>

<p>A collection of xnum bitter compounds, suitable for high-throughput and high-content screening;</p>

<p>Feed additives are a core component of the modern feed industry. They refer to small or trace substances added during the processing and application of feed. Although the dosage is extremely small (usually less than 1%), they play a significant role in enhancing feed nutrition, improving animal production performance, safeguarding animal health, optimizing the quality of livestock products and reducing breeding costs. TargetMol has collected 256 types of feed additives, which can be applied in feed development and other research fields.</p>

<p>A collection of 79 phosphatase inhibitors with known activity;</p>

<p>A unique collection of xnum approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 972 pediatric drugs for high-throughput screening and high-content screening.</p>

<p>A unique collection of xnum compounds for high-throughput screening and high-content screening,</p>

<p>A unique collection of xnum pesticide-related compounds for high throughput screening (HTS) and high content screening (HCS);</p>

<p>xnum macrocyclic compounds of known activity for high-throughput, high-content screening;</p>

<p>A unique collection of xnum PPI-related compounds for drug screening;</p>

<p>A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl，2-Chloropropionyl，Acryloyl，sulfonyl fluoride, alkyne，</p>

<p>The cysteine covalent library contains xnum compounds.</p>

<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>

<p>A unique collection of xnum annotated bioactive compounds with clear targets, suitable for phenotypic screening；</p>

<p>A unique collection of xnum types of multi-target compounds for high throughput screening (HTS) and high content screening (HCS);</p>

<p>791 peptides can be used in peptide drug development and signaling transduction and mechanism study;</p>

<p>55 species of cyclic peptide molecules for high-throughput and high-content screening;</p>

<p>A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of xnum potential anti-fibrosis compounds, can be used in HTS and HCS;</p>

<p>A unique collection of 97 beta-lactam compounds, can be used in HTS and HCS;</p>

<p>A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.</p>

<p>A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.</p>

<p>A unique collection of xnum of orally active compounds for high-throughput screening and high-content screening.</p>

<p>1163 compounds associated with depression that can be used for high-throughput and high-content screening</p>

<p>A Collection of xnum inactive ingredients from FDA-approved drugs.</p>

<p>A unique collection of xnum of cosmetic ingredient compounds.</p>

<p>A collection of 195 Baijiu components, suitable for high-throughput and high-content screening.</p>

<p>Vitamins are a class of trace organic small molecules essential for maintaining normal life activities in the human body. Most of them cannot be synthesized by the body itself or the synthesis amount is insufficient, and must rely on external intake. Vitamins do not provide energy and do not form cell structure, but as key metabolic regulatory substances, they play irreplaceable physiological functions in the body: for example, B vitamins act as coenzymes to participate in energy and material metabolism; Vitamin C has a powerful antioxidant effect and promotes the synthesis of collagen. Vitamin A maintains visual and immune functions; Vitamin D regulates calcium-phosphorus balance and bone health. Vitamin E protects cell membranes from oxidative damage. Vitamin K plays a core role in blood coagulation and bone metabolism. TargetMol includes 90 kinds of natural vitamins and their derivatives and analogues. All compounds have undergone strict quality control, with high purity and detailed information, and are provided in standardized formats. It is an effective tool resource for promoting research in the field of vitamins and related areas, facilitating the development of new drugs, exploration of disease mechanisms, and innovation of functional products.</p>

<p>The library consists of more than 4,000 members belonging 22 scaffolds (average 180 compounds per scaffold).</p>