CAS 10416-59-8

N,O-Bis(triméthylsilyl)acétamide

Description :

N,O-Bis(triméthylsilyl)acétamide, communément appelé BSA, est un composé chimique caractérisé par son utilisation en tant qu'agent de dérivatisation en chimie analytique, en particulier en chromatographie en phase gazeuse et en spectrométrie de masse. Il présente une structure comprenant deux groupes triméthylsilyl attachés aux atomes d'azote et d'oxygène d'un moiety d'acétamide, améliorant sa capacité à former des dérivés stables avec des groupes fonctionnels polaires. Ce composé est typiquement un liquide incolore à jaune pâle avec un point d'ébullition relativement bas, ce qui le rend adapté à diverses applications en synthèse organique et en préparation d'échantillons. Le BSA est connu pour sa capacité à améliorer la volatilité et la stabilité thermique des analytes, facilitant leur détection et leur quantification. De plus, il est relativement stable dans des conditions de laboratoire standard, mais doit être manipulé avec précaution en raison de sa réactivité avec l'humidité et de son potentiel à libérer du triméthylsilanol lors de l'hydrolyse. Dans l'ensemble, N,O-Bis(triméthylsilyl)acétamide est un outil précieux dans le domaine de la chimie analytique pour améliorer l'analyse de mélanges complexes.

Formule : C₈H₂₁NOSi₂

InChI : InChI=1S/C8H21NOSi2/c1-8(9-11(2,3)4)10-12(5,6)7/h1-7H3

Code InChI : InChIKey=SIOVKLKJSOKLIF-UHFFFAOYSA-N

SMILES : N([Si](C)(C)C)=C(O[Si](C)(C)C)C

Synonymes :

• Acetimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester
• BSA
• Bis trimethyl silyl acetamide
• Bis(trimethylsilyl)acetamide
• Bis(trimethylsilyl)acetimidate
• Dynasylan Bsa
• Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester
• Ls 7270
• N,O-BIS-(Trimethyl silyl)-acetamide
• N,O-Bis(trimethylsilyl)aectamide
• N,O-Bis-trimethylsilylacetoamide
• N,O-Di(trimethylsilyl)acetamide
• N-(Trimethylsilyl)acetimidic acid trimethylsilyl ester
• N-(Trimethylsilyl)ethanimidic acid trimethylsilyl ester
• NO-Bis (trimethylsilyl) acetamide
• O,N-Bis(trimethylsilyl)acetamide
• trimethylsilyl (1E)-N-(trimethylsilyl)ethanimidoate
• trimethylsilyl N-(trimethylsilyl)ethanimidoate
• trimethylsilyl N-trimethylsilylacetamidate

N,O-Bis(trimethylsilyl)acetamide [Trimethylsilylating Agent]

CAS : 10416-59-8

Formule : C₈H₂₁NOSi₂

Degré de pureté : >80.0%(GC)

Couleur et forme : Colorless to Light yellow clear liquid

Masse moléculaire : 203.43

Ref: 3B-B0511

N,O-Bis(trimethylsilyl)acetamide (25% in Acetonitrile) [Trimethylsilylating Reagent, for NH2 compounds]

CAS : 10416-59-8

Couleur et forme : Colorless to Light yellow clear liquid

Ref: 3B-B0510

N,O-Bis(trimethylsilyl)acetamide Kit BSA 1 mL × 8 / Reaction vial, capacity 2 mL × 8

CAS : 10416-59-8

Degré de pureté : >80.0%(GC)

Couleur et forme : Colorless to Light yellow clear liquid

Ref: 3B-B0911

BSA [=N,O-Bis(trimethylsilyl)acetamide] [for Gas Chromatography]

CAS : 10416-59-8

Formule : C₈H₂₁NOSi₂

Degré de pureté : >80.0%(GC)

Couleur et forme : Colorless to Light yellow clear liquid

Masse moléculaire : 203.43

Ref: 3B-A5601

TMS-BA [=N,O-Bis(trimethylsilyl)acetamide] (25% in Acetonitrile) [for Gas Chromatography]

CAS : 10416-59-8

Degré de pureté : No impurity higher than Isopropyl myristate(50 ppm) after 5 min + hold up time

Couleur et forme : Colorless to Light yellow clear liquid

Ref: 3B-A5602

N,O-Bis(trimethylsilyl)acetamide, 95%

CAS : 10416-59-8

N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloi

Formule : C₈H₂₁NOSi₂

Degré de pureté : 95%

Couleur et forme : Clear, colorless to pale yellow, Liquid

Masse moléculaire : 203.43

Ref: 02-L00183

N,O-Bis(Trimethylsilyl)Acetamide

CAS : 10416-59-8

Formule : C₈H₂₁NOSi₂

Degré de pureté : 95%

Couleur et forme : Liquid

Masse moléculaire : 203.4294

Ref: IN-DA00399B

N,O-Bis(trimethylsilyl)acetamide

CAS : 10416-59-8

Formule : C₈H₂₁NOSi₂

Degré de pureté : (GC) ≥ 94.0%

Couleur et forme : Clear, colourless to light yellow liquid

Masse moléculaire : 203.43

Ref: 7W-GK3085

Trimethylsilyl N-(trimethylsilyl)acetimidate

CAS : 10416-59-8

Trimethylsilyl N-(trimethylsilyl)acetimidate

Formule : C₈H₂₁NOSi₂

Degré de pureté : 97%

Couleur et forme : clear. almost colourless liquid

Masse moléculaire : 203.42943g/mol

Ref: 54-OR5155A

N,O-Bis(trimethylsilyl)acetamide Kit TMS-BA (25% in Acetonitrile) 1 mL × 8 / Reaction vial, capacity 2 mL × 8 [Trimethylsilylating Reagent, for NH2 compounds]

CAS : 10416-59-8

Couleur et forme : Colorless to Light yellow clear liquid

Ref: 3B-T0691

N,O-Bis(trimethylsilyl)acetamide (BSA)

CAS : 10416-59-8

S02375 - N,O-Bis(trimethylsilyl)acetamide (BSA)

Formule : C₈H₂₁NOSi₂

Degré de pureté : >97%

Couleur et forme : Clear

Masse moléculaire : 203.432

Ref: 10-S02375

N,O-Bis(trimethylsilyl) Acetamide

CAS : 10416-59-8

Formule : C₈H₂₁NOSi₂

Masse moléculaire : 203.43

Ref: 4Z-A-133025

N,O-Bis(trimethylsilyl)acetamide

Produit contrôlé

CAS : 10416-59-8

Applications N,O-Bis(trimethylsilyl)acetamide is used as a reagent in the synthesis of 4'-spirocyclic phosphono-nucleosides as potential inhibitors of hepatitis C virus NS5B polymerase. Also used as a reagent in the microwave-assisted synthesis of purine nucleosides as selective cholinesterase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dang, Q., et al.: Tetrahedron Lett., 55, 4407 (2014); Schwarz, S., et al.: Org. Biomol. Chem., 12, 2446 (2014)

Formule : C₈H₂₁NOSi₂

Couleur et forme : Neat

Masse moléculaire : 203.43

Ref: TR-B588675

N,O-Bis(trimethylsilyl) acetamide

CAS : 10416-59-8

N,O-Bis(trimethylsilyl) acetamide is a protein that is used as a reagent for the detection of integrin receptors. It can be used to identify human immunoglobulin and human serum proteins. This compound has been shown to be pluripotent in cells, which means that it can differentiate into any type of cell. N,O-Bis(trimethylsilyl) acetamide has been shown to have surfactant properties and can be used as an alternative in toxicity studies. This compound has been shown to be toxic to bowel disease cells when tested with a dose of 3mg/mL. The disulfide bond within this molecule may be important for its biological activity. Synchronous fluorescence spectroscopy and plasma mass spectrometry are two methods that have been used to study the structure of this molecule. Electrochemical impedance spectroscopy is another method that has been used in the structural analysis of this molecule.

Formule : C₈H₂₁NOSi₂

Degré de pureté : Min. 95 Area-%

Couleur et forme : Colorless Yellow Clear Liquid

Masse moléculaire : 203.43 g/mol

Ref: 3D-FB03098

N,O-BIS(TRIMETHYLSILYL)ACETAMIDE

CAS : 10416-59-8

Trimethylsilyl Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
Alkyl Silane - Conventional Surface Bonding
Aliphatic, fluorinated aliphatic or substituted aromatic hydrocarbon substituents are the hydrophobic entities which enable silanes to induce surface hydrophobicity. The organic substitution of the silane must be non-polar. The hydrophobic effect of the organic substitution can be related to the free energy of transfer of hydrocarbon molecules from an aqueous phase to a homogeneous hydrocarbon phase. A successful hydrophobic coating must eliminate or mitigate hydrogen bonding and shield polar surfaces from interaction with water by creating a non-polar interphase. Although silane and silicone derived coatings are in general the most hydrophobic, they maintain a high degree of permeability to water vapor. This allows coatings to breathe and reduce deterioration at the coating interface associated with entrapped water. Since ions are not transported through non-polar silane and silicone coatings, they offer protection to composite structures ranging from pigmented coatings to rebar reinforced concrete. A selection guide for hydrophobic silanes can be found on pages 22-31 of the Hydrophobicity, Hydrophilicity and Silane Surface Modification brochure.
Bis(Trimethylsilyl)acetamide; N,O-Bis(trimethylsilyl)acetamide; Trimethylsilyl-N-Trimethylsilylacetamidate; BSA
More reactive than SIH6110.0Releases neutral acetamide upon reactionBoth silyl groups usedUsed for silylation in analytical applicationsReactions catalyzed by acidForms enol silyl ethers in ionic liquidsNafion SAC-13 has been shown to be a recyclable catalyst for the trimethylsilylation of primary, secondary, and tertiary alcohols in excellent yields and short reaction timesSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

Formule : C₈H₂₁NOSi₂

Degré de pureté : 95%

Couleur et forme : Straw Liquid

Masse moléculaire : 203.43

Ref: 3H-SIB1846.0

N,O-Bis-(Trimethylsilyl) Acetamide (BSA) extrapure, 95%

CAS : 10416-59-8

Formule : C₈H₂₁NOSi₂

Degré de pureté : min. 95.0%

Couleur et forme : Clear, Colourless to pale yellow, Liquid

Masse moléculaire : 203.43

Ref: SR-26477