![Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F382836-5-o-44-dimethoxytrityl-5-methyl-n4-benzoyl-2-deoxycytidine-3-2-cyanoethyl-n-n-diisopropyl-phosphoramidite.webp&w=3840&q=75)
CAS 105931-57-5
:Cytidine, N-benzoyl-5′-O-[bis(4-méthoxyphényl)phénylméthyl]-2′-désoxy-5-méthyl-, 3′-[2-cyanoéthyl N,N-bis(1-méthyléthyl)phosphoramidite]
Description :
Cytidine, N-benzoyl-5′-O-[bis(4-méthoxyphényl)phénylméthyl]-2′-désoxy-5-méthyl-, 3′-[2-cyanoéthyl N,N-bis(1-méthyléthyl)phosphoramidite] est un composé chimique complexe principalement utilisé dans le domaine de la chimie des acides nucléiques, en particulier dans la synthèse des oligonucleotides. Cette substance présente une base de cytidine, qui est un nucléoside composé d'un cycle de pyrimidine et d'un sucre ribose, modifié avec un groupe benzoyle et une partie phosphoramidite. La présence du groupe bis(4-méthoxyphényl)phénylméthyle améliore sa stabilité et sa solubilité, le rendant adapté à diverses applications biochimiques. La fonctionnalité de phosphoramidite cyanoéthyle permet des réactions de couplage efficaces lors de la synthèse d'oligonucleotides, facilitant la formation de liaisons phosphodiester. Ce composé se caractérise par sa capacité à participer à des réactions sélectives, contribuant au développement de méthodologies synthétiques en biologie moléculaire et en ingénierie génétique. Son numéro CAS, 105931-57-5, sert d'identifiant unique à des fins réglementaires et de recherche.
Formule :C47H54N5O9P
InChI :InChI=1S/C47H54N5O8P/c1-32(2)52(33(3)4)61(58-28-14-27-48)60-41-29-43(51-30-34(5)44(50-46(51)54)49-45(53)35-15-10-8-11-16-35)59-42(41)31-57-47(36-17-12-9-13-18-36,37-19-23-39(55-6)24-20-37)38-21-25-40(56-7)26-22-38/h8-13,15-26,30,32-33,41-43H,14,28-29,31H2,1-7H3,(H,49,50,53,54)/t41-,42+,43+,61?/m0/s1
Code InChI :InChIKey=AGMUHEZFYUECLW-QUZMAVINSA-N
SMILES :C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@@H](O1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
Synonymes :- 4: PN: US20030212017 PAGE: 17 claimed DNA
- 5'-O-(4,4'-Dimethoxytrityl)-5-Methyl-N4-Benzoyl-2'-Deoxycytidine-3'-(2-Cyanoethyl-N,N-Diisopropyl)Phosphoramidite
- 5: PN: US20030211606 PAGE: 17 claimed DNA
- 6: PN: US20040014048 PAGE: 18 claimed DNA
- 6: PN: US20040014049 PAGE: 18 claimed DNA
- 7: PN: US20030198965 PAGE: 17 claimed DNA
- 7: PN: US20040014047 PAGE: 18 claimed DNA
- 80: PN: US20040005707 PAGE: 18 claimed DNA
- 8: PN: US20040005565 PAGE: 17-22 claimed DNA
- 8: PN: US20040005569 PAGE: 20 claimed DNA
- 8: PN: US20040005570 PAGE: 18 claimed DNA
- 8: PN: US20040006029 PAGE: 20 claimed DNA
- 8: PN: US20040006030 PAGE: 20 claimed DNA
- 8: PN: US20040014050 PAGE: 18 claimed DNA
- 8: PN: US20040014051 PAGE: 20 claimed DNA
- 8: PN: US20040014699 PAGE: 18 claimed DNA
- 8: PN: WO03106645 PAGE: 64 claimed DNA
- Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- N4-Benzoyl-5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite
- DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite
- 5'-O-DMT-N4-Benzoyl-2'-Deoxy-5-Methylcytidine-CE Phosphoramidite
- 5-Me-DMT-dC(Bz)-CE
- N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-deoxycytidine-3'-cyanoethyl Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE Phosphoramidite
- 8: PN: US20040014050 PAGE
- 5-methyldeoxycytidine-ce*phosphoramidite for cycl
- 5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite
- US20040006030 PAGE: 20 claimed DNA
- 5'-Dimethoxytrityl-N-benzoyl-5-methyl-2'-deoxyCytidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- 5-Me-dCBzPhosphoramidite
- deoxy N-Bz 5-Me Cytidine Amidite
- 2'-deoxycytidine-3'-cyanoethyl
- Phosphoramidite
- N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-tetrahydrofuran-2-yl]-5-methyl-2-oxo-pyrimidin-4-yl]benzamide
- N-blocked-5'-O-DMT CED methyldeoxycytidine phosphoramidite
- 5-Me-DMT-dC(Bz)-CE Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
- 5'-O-(4,4'-DiMethoxytrityl)-N4-benzoyl-2'-deoxy-5-Methylcytidine-3'- O-(O-2-cyanoethyl-N,N-diisopropylaMino) phosphoraMidite
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-cytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- DMT-5Me-dC(Bz)-CE Phosphoramidite
- N4-benzoyl-5-methyl-5'-O-(4, 4'-dimethoxytrityl)-
- Bz-5-Me-dC phosphoramidite
- 5-Me Bz dC Beta-Cyanoethyl Phosphoramidite (500 mg) (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
- 5-Me-dC CE Phosphoramidite
- Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
- N -Benzoyl-5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl-N,N-diisopropylphosphoramidite(DMT-5-MedC(bz)phosphoramidite)
- Voir plus de synonymes
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8 produits concernés.
5-Me Bz dC β-Cyanoethyl Phosphoramidite (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C47H54N5O8PCouleur et forme :White PowderMasse moléculaire :847.3715'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
CAS :Formule :C47H54N5O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :847.9341DMT-5Me-dC(Bz)-CE Phosphoramidite
CAS :DMT-5Me-dC(Bz)-CE PhosphoramiditeDegré de pureté :99%Masse moléculaire :847.93g/molDMT-5Me-dC(Bz)-CE Phosphoramidite
CAS :DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.Formule :C47H54N5O8PCouleur et forme :SolidMasse moléculaire :847.93DMT-5-Me-dC(Bz) Phosphoramidite
CAS :Formule :C47H54N5O8PDegré de pureté :>95.0%(HPLC)Couleur et forme :White to Yellow powder to crystalMasse moléculaire :847.95N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
CAS :<p>Nucleoside phosphoramidites are widely used as building blocks in the chemical synthesis of oligonucleotides. The use of a chemical synthesis rather than an enzymatic one allows bespoke oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with the 5’ hydroxyl of the next nucleoside in the desired sequence. The reaction is usually catalysed by 1H-tetrazole or 4,5-dicyanoimidazole in acetonitrile. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, also called N4-Bz-5'-DMT-5-Me-dC phosphoramidite, is used in the synthesis of 2’-deoxy-5-methylcytidine-containing oligonucleotides as antisense drugs.</p>Formule :C47H54N5O8PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :847.93 g/mol
