CAS 1069046-00-9

ASB 14780New

CAS : 1069046-00-9

ASB 14780New is a novel small molecule that has been shown to reduce the inflammatory response by inhibiting the production of inflammatory cells and decreasing the accumulation of collagen. ASB 14780New targets senescent cells, which are cells that have stopped dividing and accumulate in various tissues and organs. The drug also affects markers present in cytosolic extracts from muscle cells, such as growth factor-β1 (GF-β1) and cox-1. It has been shown to inhibit cholesterol absorption and promote its excretion through the bile. ASB 14780New also reduces inflammation caused by carbon tetrachloride or an experimental diet rich in cholesterol.
ASB 14780New is being studied for its potential therapeutic effects in Alzheimer's disease, where it may be able to reduce inflammation by targeting senescent cells.

Formule : C₃₁H₂₇NO₃·C₄H₁₁NO₃

Degré de pureté : Min. 95%

Masse moléculaire : 582.7 g/mol

Ref: 3D-USB04600

ASB 14780

CAS : 1069046-00-9

Potent cPLA2α inhibitor with 20 nM IC50. No sPLA2α inhibition at 10 µM. Reduces inflammation and liver fibrosis. Orally bioavailable.

Formule : C₃₅H₃₈N₂O₆

Couleur et forme : Solid

Masse moléculaire : 582.697

Ref: TM-T37842